41888-91-9Relevant articles and documents
Synthesis of a precursor of bioactive pentapeptide OGP-(10-14) and the fragment of enkephalin catalyzed by MCM-22 immobilized or free proteases in organic solvents
Liu, Ping,Ye, Yun-Hua,Tian, Gui-Ling,Lee, Kin-Sing,Wong, Man-Sau,Lo, Wai-Hung
, p. 726 - 732 (2007/10/03)
Full enzymatic synthesis of a precursor of osteogenic growth peptide fragment (10-14), Z-Tyr-Gly-Phe-Gly-Gly-OEt, was accomplished using immobilized proteases on molecular sieve MCM-22 by adsorption as catalyst via 3+2 synthetic route for the first rime. The reuse time of immobilized enzyme was dependent on concrete reaction system. Compared with free enzyme, the reaction rate catalyzed by immobilized enzyme was remarkably enhanced and its synthetic yield was also increased in most cases. The effects of water content and the added amount of Et3N on synthesis of fragments of bioactive peptides including OGP-(10-14) and enkephalin by immobilized enzymes were different from free enzyme.
Enzymatic synthesis of oligopeptides in mixed reverse micelles
Xing, Guo-wen,Liu, Dao-jun,Ye, Yun-hua,Ma, Ji-ming
, p. 1971 - 1974 (2007/10/03)
Some oligopeptide derivatives were successfully synthesized in 56-88% yield by α-chymotrypsin in AOT-Brij30/n-heptane mixed reverse micelles. The reaction conditions such as W0 value, reaction time and the concentration of enzyme in the water p
Facile One-Pot Amidation of Carboxylic Acids by Amines Catalyzed by Triphenylstibine Oxide/Tetraphosphorus Decasulfide (Ph3SbO/P4S10)
Nomura, Ryoki,Nakano, Takahiro,Yamada, Yasuhiro,Matsuda, Haruo
, p. 4076 - 4078 (2007/10/02)
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