16679-94-0

Basic information

• Product Name: Z-TYR-OET
• Synonyms: N-ALPHA-CARBOBENZOXY-L-TYROSINE ETHYL ESTER;Z-TYR-OET;Z-L-TYROSINE ETHYL ESTER;CBZ-L-TYROSINE ETHYL ESTER;(S)-ethyl 2-(benzyloxycarbonylamino)-3-(4-hydroxyphenyl)propanoate;CBZ-Tyr-OEt;Z-L-Tyr-OEt;Z-L-tyrosine ethyl ester≥ 98% (HPLC)
• CAS NO: 16679-94-0
• Molecular Formula: C₁₉H₂₁NO₅
• Molecular Weight: 343.37
• Mol File: 16679-94-0.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Z-TYR-OET(CAS DataBase Reference)
• NIST Chemistry Reference: Z-TYR-OET(16679-94-0)
• EPA Substance Registry System: Z-TYR-OET(16679-94-0)

Safety Data

• Hazardous Substances Data: 16679-94-0(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Upstream product

• 4089-07-0 L-tyrosine ethyl ester monohydrochloride 
• 501-53-1 benzyl chloroformate 
• 100-51-6 benzyl alcohol 
• 60-18-4 L-tyrosine 
• 64-17-5 ethanol 
• 205866-50-8 (S)-3-benzyloxycarbonyl-4-(4-hydroxyphenyl)methyloxazolidin-5-one 
• 64645-55-2 N-(benzyloxycarbonyl)-O-<(tert-butoxycarbonyl)glycyl>-L-tyrosine ethyl ester 
• 5618-98-4 N-α-benzyloxycarbonyl-DL-tyrosine 
• 949-67-7 L-tyrosine ethyl ester 

Downstream Products

• 66328-78-7 N-(benzyloxycarbonyl)-O-tert-butyltyrosine ethyl ester 
• 64645-55-2 N-(benzyloxycarbonyl)-O-<(tert-butoxycarbonyl)glycyl>-L-tyrosine ethyl ester 
• 34695-67-5 Z-Tyr-Gly-Gly-OEt 
• 771-61-9 2,3,4,5,6-pentafluorophenol 
• 14719-37-0 ethyl 2-(tert-butoxycarbonylamino)acetate 
• 1164-16-5 Z-L-Tyr-OH 
• 153077-03-3 (S)-benzyl (1-(4-hydroxyphenyl)-3-oxopropan-2-yl)carbamate 
• 41888-91-9 N-CBZ-L-tyrosylglycine ethyl ester 
• 1033470-93-7 N-benzyloxycarbonyl-O'-(prop-2-enyl)-L-tyrosine ethyl ester 
• 158043-54-0 (S)-N-Benzyloxycarbonyl-N'-(2-aminoethyl)-1-(4-ethoxybenzyl)ethylenediamine 
• 158043-52-8 N-benzyloxycarbonyl-[S-1-(4-ethoxybenzyl)-2-hydroxyethyl]carboxamide 
• 16879-89-3 N-Benzyloxycarbonyl-O-tert.-butyl-L-tyrosin-(4-nitro-benzylester) 
• 16879-86-0 N-Benzyloxycarbonyl-L-tyrosin-(4-nitro-benzylester) 
• 4727-00-8 O-t-Butyl-L-tyrosine 

Relevant articles and documents

Cleavage of benzyloxycarbonyl-5-oxazolidinones to α-benzyloxycarbonylamino-α-alkyl esters by alcohols and sodium hydrogen carbonate

The reaction of benzyloxycarbonyl-5-oxazolidinones with alcohols and sodium hydrogen carbonate to afford the corresponding benzyloxycarbonyl esters is described.

An Improved Preparation of Oxazolidin-2-one Chiral Auxiliaries

Reduction of carbamate-blocked amino esters by lithium borohydride (made in situ from sodium borohydride and lithium iodide) forms chiral 4-substituted oxazolidin-2-ones directly. The presence of iodide in the reaction mixture appears to promote the cyclization of the intermediate alkoxyborohydride. This provides a route to these important chiral auxiliaries, employing less hazardous reagents and simpler reaction conditions than do most existing methods.

PAPAIN-ASSISTED RESOLUTION OF NATURAL AND XENOBIOTIC α-AMINO ACIDS

A new and convenient method for the preparation of pure enantiomers of α-amino acids is described.Industrial papain, catalyzes the synthesis of L-Z-amino acid ethyl esters in ethanolic medium, with good yields.These esters are obtained from DL-Z-amino acids with 100percent optical purity.Unreactive D-Z-amino acids are readily isolated from reaction medium.Physical constants of natural and xenobiotic L-Z-amino acid esters and D-Z-amino acids are described.