42429-27-6

Basic information

• Product Name: L-Prolinamide hydrochloride
• Synonyms: L-PYRROLIDINE-2-CARBOXYLIC ACID AMIDE HYDROCHLORIDE;L-PROLINAMIDE HCL;L-(-)-PROLINAMIDE HYDROCHLORIDE;L-PROLINAMIDE HYDROCHLORIDE;L-PROLINE AMIDE HYDROCHLORIDE;H-L-PRO-NH2 HCL;H-PRO-NH2 HCL;(S)-Pyrrolidine-2-carboxamide hydrochloride
• CAS NO: 42429-27-6
• Molecular Formula: C₅H₁₀N₂O*ClH
• Molecular Weight: 150.61
• EINECS: 255-818-2
• Product Categories: AMINOACIDS DERIVATIVES;Naphthyridine,Quinoline;Amino Acids;I - Z;Modified Amino Acids;Amino Acid Derivatives;Peptide Synthesis;Proline
• Mol File: 42429-27-6.mol
• Article Data: 6

Chemical Properties

• Melting Point: 178-182 °C
• Boiling Point: 303.6 ºC at 760 mmHg
• Flash Point: 137.4 ºC
• Appearance: /
• Vapor Pressure: 0.000923mmHg at 25°C
• Storage Temp.: -15°C
• BRN: 3693546
• CAS DataBase Reference: L-Prolinamide hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: L-Prolinamide hydrochloride(42429-27-6)
• EPA Substance Registry System: L-Prolinamide hydrochloride(42429-27-6)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 3-10
• Hazardous Substances Data: 42429-27-6(Hazardous Substances Data)

Usage

General Description

L-Prolinamide hydrochloride is a chemical compound that is often used in various pharmaceutical and research applications. It is the hydrochloride salt form of L-Prolinamide, which is an amino acid derivative. L-Prolinamide hydrochloride is known for its potential medicinal properties, particularly in the field of drug development and synthesis. L-Prolinamide hydrochloride has been studied for its potential role in the treatment of various conditions such as inflammatory diseases and certain types of cancer. Its unique chemical properties make it a valuable component in the development of new pharmaceutical products.

InChI:InChI=1/C5H10N2O.ClH/c6-5(8)4-2-1-3-7-4;/h4,7H,1-3H2,(H2,6,8);1H

Upstream product

• 2133-40-6 L-proline methyl ester monohydrochloride 
• 3392-10-7 tert-butoxycarbonyl-L-proline N-hydroxysuccinimide ester 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 
• 147-85-3 L-proline 
• 35150-07-3 (S)-tert-butyl 2-carbamoylpyrrolidine-1-carboxylate 
• 76409-77-3 Ac-Aib-L-Pro-NH₂ 

Downstream Products

• 83871-06-1 N-benzyloxycarbonyl-L-phenylalanyl-L-prolinamide 
• 82935-40-8 (S)-(-)-1-trityl-2-pyrrolidinecarboxamide 
• 73385-89-4 N-(tert-butyloxycarbonyl)-L-4-nitrophenylalanyl-L-prolinamide 
• 50654-97-2 N(α)-t-butoxycarbonyl-D-histidyl-L-prolineamide 
• 29133-55-9 N(α)-t-butoxycarbonyl-L-histidyl-L-prolineamide 
• 177657-33-9 N-MOC-L-pro-NH₂ 
• 185141-47-3 [(R)-2-((S)-2-Carbamoyl-pyrrolidin-1-yl)-1-(4-methoxy-benzylsulfanylmethyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester 
• 207557-35-5 (S)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile 
• 1163791-10-3 4-[(S)-2-({5-[2-((S)-2-carbamoyl-pyrrolidin-1-yl)-2-oxo-ethoxy]-1-phenyl-1H-pyrazole-3-carbonyl}-amino)-4-carboxy-butyryl]-piperazine-1-carboxylic acid ethyl ester 
• 1380490-70-9 (S)-1-(phenylcarbamoyl)pyrrolidine-2-carboxamide 
• 226249-98-5 2-carbamoyl-1-(4-chlorobenzyl)pyrrolidine 
• 579491-20-6 [(S)-2-((S)-2-Carbamoyl-pyrrolidin-1-yl)-1-(4-hydroxy-2,6-dimethyl-benzyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester 
• 155540-07-1 acryloyl-L-prolylamide 
• 77400-63-6 (S)-2-[(Z)-1-((S)-2-Carbamoyl-pyrrolidine-1-carbonyl)-2-phenyl-vinylcarbamoyl]-5-oxo-pyrrolidine-1-carboxylic acid benzyl ester 

Relevant articles and documents

Synthesis, characterization and conformation of an undecapeptide hydrazide of the N-terminal sequence of alamethicin

-

NOVEL 5-SUBSTITUTED INDOLE DERIVATIVES AS DIPEPTIDYL PEPTIDASE IV (DPP-IV) INHIBITORS

The present invention relates to 5-substituted indole derivatives of formula (I): having inhibitory potential of dipeptidyl peptidase IV (DPP IV) enzyme where x and R1 are defined as defined in the specification

Synthesis of α-amino dithioesters and endothiodipeptides

The α-amino ester hydrochlorides (1) are converted into N-protected α-amino amides (3), α-amino thioamides (4) and α-amino dithiomethylesters (5). Condensation of 5 with the alkali salts of α-amino acids gives rise to the endothiodipeptide alkali salts (7). Johann Ambrosius Barth 1996.