427-63-4

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Basic information

Product Name: GEODIN
Synonyms: SPIRO[BENZOFURAN-2(3H),1'-[2,5]CYCLOHEXADIENE]-2'-CARBOXYLIC ACID, 5,7-DICHLORO-4-HYDROXY-6'-METHOXY-6-METHYL-3,4'-DIOXO-, METHYL ESTER;GEODIN;(+)-ESTIN;Estin, (+)-5,7-dichloro-4-hydroxy-6-methoxy-6-methyl-3,4-dioxo-spiro[benzofuran-2(3H),1-[2,5]cyclohexadiene]-2-carboxylic acid methyl ester;(1R)-3',4-Dioxo-4'-hydroxy-5',7'-dichloro-6-methoxy-6'-methylspiro[2,5-cyclohexadiene-1,2'(3'H)-benzofuran]-2-carboxylic acid methyl ester;(1R)-3',4-Dioxo-4'-hydroxy-5',7'-dichloro-6'-methyl-6-methoxyspiro[2,5-cyclohexadiene-1,2'(3'H)-benzofuran]-2-carboxylic acid methyl ester;(R)-5,7-Dichloro-4-hydroxy-6'-methoxy-6-methyl-3,4'-dioxospiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid methyl ester;d-Geodin
CAS NO:427-63-4
Molecular Formula: C17H12Cl2O7
Molecular Weight: 399.18
EINECS: N/A
Product Categories: N/A
Mol File: 427-63-4.mol
Article Data: 1

Chemical Properties

Melting Point: 235℃
Boiling Point: 652.1 °C at 760 mmHg
Flash Point: 348.2 °C
Appearance: /
Density: 1.61 g/cm³
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: GEODIN(CAS DataBase Reference)
NIST Chemistry Reference: GEODIN(427-63-4)
EPA Substance Registry System: GEODIN(427-63-4)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 427-63-4(Hazardous Substances Data)

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Spiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylicacid, 5,7-dichloro-4-hydroxy-6'-methoxy-6-methyl-3,4'-dioxo-, methyl ester,(1'R)-
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10000 Metric Ton/Month
Henan Wentao Chemical Product Co., Ltd.
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Geodin
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Henan Allgreen Chemical Co.,Ltd
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GEODIN
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ZHEJIANG JIUZHOU CHEM CO.,LTD
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GEODIN
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cfm Oskar Tropitzsch
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427-63-4 Usage

Description

(+)-Geodin is a fungal metabolite. It increases the fibrinolytic activity of bovine aortic endothelial cells (BAECs) when used at concentrations ranging from 50 to 150 μM. (+)-Geodin (1-100 μg/ml) also increases 2-deoxyglucose uptake by rat adipocytes.

Uses

Geodin is an inhibitor of plasminogen activator inhibitor (PAI-1).

Check Digit Verification of cas no

The CAS Registry Mumber 427-63-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,2 and 7 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 427-63:
(5*4)+(4*2)+(3*7)+(2*6)+(1*3)=64
64 % 10 = 4
So 427-63-4 is a valid CAS Registry Number.

427-63-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name	methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate

1.2 Other means of identification

Product number	-
Other names	Geodin

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:427-63-4 SDS

427-63-4Upstream product

2151-16-8 methyl 2-(3,5-dichloro-2,6-dihydroxy-4-methylbenzoyl)-5-hydroxy-3-methoxybenzoate

427-63-4Downstream Products

102173-59-1 methyl 2,4-dichloroasterrate

427-63-4Relevant articles and documents

Purification and characterization of dihydrogeodin oxidase from a fungal strain of Aspergillus terreus producing (+)-geodin

Fujii,Iijima,Ebizuka,Sankawa

, p. 337 - 340 (2007/10/02)

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