430-91-1Relevant articles and documents
A new approach to the synthesis of (Z)-2-fluoro-2-alkenals via Wittig-type carbonyl condensation reactions of 2-(fluoromethyl)-4,4,6-trimethyl-1,3-oxazine phosphonium bromide
Kajjout, Mohammed,Smietana, Micha?l,Leroy, Jacques,Rolando, Christian
, p. 1658 - 1660 (2013/03/29)
We report here the transformation of aldehydes to their (Z)-α-fluoro-α,β-unsaturated aldehyde homologs by condensation with the phosphonium salt of the Meyer's oxazine obtained from bromofluoroacetonitrile. After methylation with trimethyloxonium tetrafluoroborate the quaternized oxazine is cleanly reduced to mostly Z 2-fluoro-2-alkenals by sodium borohydride at room temperature. This methodology is compatible with usual protecting groups and affords an efficient access to functionalized mostly Z 2-fluoro-2-alkenals derived from natural products and their corresponding (Z)-2-fluoro-2-alkenols.
2-Fluoro-2-cyanoethenyl cyclopropane carboxylates as pesticides
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, (2008/06/13)
Novel cyclopropanecarboxylates in all possible isomeric forms or mixtures thereof of the formula STR1 with a 1R,cis or 1R,trans structure and wherein X is a halogen, R is selected from the group consisting of (A) optionally unsaturated alkyl of 2 to 12 ca