43005-49-8

Basic information

• Product Name: 6-amino-2-(methylsulfanyl)-5-nitrosopyrimidin-4(1H)-one
• Synonyms: 4(3H)-pyrimidinone, 6-amino-2-(methylthio)-5-nitroso-; 6-Amino-2-(methylsulfanyl)-5-nitrosopyrimidin-4(3H)-one
• CAS NO: 43005-49-8
• Molecular Formula: C₅H₆N₄O₂S
• Molecular Weight: 186.1917
• Mol File: 43005-49-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 277.2°C at 760 mmHg
• Flash Point: 121.4°C
• Density: 1.79g/cm³
• Vapor Pressure: 0.0046mmHg at 25°C
• Refractive Index: 1.779
• CAS DataBase Reference: 6-amino-2-(methylsulfanyl)-5-nitrosopyrimidin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-amino-2-(methylsulfanyl)-5-nitrosopyrimidin-4(1H)-one(43005-49-8)
• EPA Substance Registry System: 6-amino-2-(methylsulfanyl)-5-nitrosopyrimidin-4(1H)-one(43005-49-8)

Safety Data

• Hazardous Substances Data: 43005-49-8(Hazardous Substances Data)

Upstream product

• 1074-41-5 2-(Methylthio)-4-hydroxy-6-aminopyrimidine 
• 1074-41-5 6-amino-2-methylsulfanylpyrimidin-4(3H)-one 

Downstream Products

• 62700-64-5 5-methylthio-[1,2,5]thiadiazolo[3,4-d]pyrimidin-7(6H)-one 

Relevant articles and documents

NOVEL N2, N4, N7, 6-TETRASUBSTITUTED PTERIDINE-2,4,7-TRIAMINE AND 2, 4, 6, 7-TETRASUBSTITUTED PTERIDINE COMPOUNDS AND METHODS OF SYNTHESIS AND USE THEREOF

Compounds as immune system modulators bearing a pteridine core are described. A pharmaceutical composition comprising the same, methods of making the same, and a method for treating or preventing autoimmunity disease using the same are described.

Syntheses of highly functionalised 6-substituted pteridines.

Methods for the synthesis of polyfunctional 6-substituted pteridines from the corresponding 6-aldehydes are described. Alkene, ester, ketone, amide, cyano, oxime, bromo, methoxy and dihydroxy functional groups have all been introduced principally through