43219-09-6 Usage
Description
1-(2-chloroethyl)-4-phenylpiperazine, a chemical compound belonging to the class of piperazine derivatives, is a psychoactive substance with potential pharmacological applications. It has demonstrated anxiolytic and anti-depressant properties in preclinical studies, making it a promising candidate for the treatment of depression and anxiety disorders. Furthermore, its potential as a radiotracer for imaging serotonin receptors in the brain holds promise for diagnosing and treating various psychiatric and neurological conditions. However, further research is necessary to fully comprehend its therapeutic potential and safety profile.
Uses
Used in Pharmaceutical Applications:
1-(2-chloroethyl)-4-phenylpiperazine is used as a pharmacological agent for its anxiolytic and anti-depressant properties, targeting the treatment of depression and anxiety disorders. Its effects have been observed in preclinical studies, indicating its potential to alleviate symptoms associated with these conditions.
Used in Substance Abuse Treatment:
1-(2-chloroethyl)-4-phenylpiperazine is also being investigated for its potential in the treatment of substance abuse disorders, offering a new avenue for research and development in addiction medicine.
Used in Diagnostic Imaging:
As a potential radiotracer for imaging serotonin receptors in the brain, 1-(2-chloroethyl)-4-phenylpiperazine could be employed in the diagnosis and treatment of various psychiatric and neurological conditions, enhancing our understanding of these disorders and improving patient care.
Used in Research and Development:
1-(2-chloroethyl)-4-phenylpiperazine serves as a valuable compound for research purposes, contributing to the advancement of knowledge in the fields of pharmacology, neuroscience, and psychiatry. Its study may lead to the discovery of novel therapeutic approaches and a better understanding of the underlying mechanisms of various psychiatric and neurological conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 43219-09-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,3,2,1 and 9 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 43219-09:
(7*4)+(6*3)+(5*2)+(4*1)+(3*9)+(2*0)+(1*9)=96
96 % 10 = 6
So 43219-09-6 is a valid CAS Registry Number.
InChI:InChI=1/C12H17ClN2/c13-6-7-14-8-10-15(11-9-14)12-4-2-1-3-5-12/h1-5H,6-11H2
43219-09-6Relevant articles and documents
Design, synthesis, and biological evaluation of structurally constrained hybrid analogues containing ropinirole moiety as a novel class of potent and selective dopamine D3 receptor ligands
Zhou, Benhua,Hong, Kwon Ho,Ji, Min,Cai, Jin
, p. 1597 - 1609 (2018/07/31)
Two series of hybrid analogues were designed, synthesized, and evaluated as a novel class of selective ligands for the dopamine D3 receptor. Binding affinities of target compounds were determined (using the method of radioligand binding assay). Compared to comparator agent BP897, compounds 2a and 2c were found to demonstrate a considerable binding affinity and selectivity for D3 receptor, and especially compound 2h was similarly potent and more selective D3R ligand than BP897, a positive reference. Thus, they may provide valuable information for the discovery and development of highly potent dopamine D3 receptor ligands with outstanding selectivity.
Versatile synthesis of disubstituted triazole library for dopamine and serotonin receptor ligands
Landge, Kamalkishor P,Seo, Yong Wan,Kwak, Jumyung,Park, Woo Kyu,Gong, Jae Yang,Lee, Hee Yoon,Koh, Hun Yeong
, p. 3101 - 3104 (2015/12/01)
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Antidiabetic piperazine derivatives, processes for their preparation and compositions containing them
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, (2008/06/13)
Piperazine derivatives of formula (I) wherein Z, X, n, Ar and i have the meanings defined herein are usefull in the treatment of pathologies associated with insulin-resistance syndrome.
