4331-29-7Relevant articles and documents
Investigating chelating sulfonamides and their use in metalloproteinase inhibitors
Tanakit, Alisa,Rouffet, Matthieu,Martin, David P.,Cohen, Seth M.
experimental part, p. 6507 - 6515 (2012/09/21)
Matrix metalloproteinase inhibitors (MMPi) utilize zinc-binding groups (ZBGs) to chelate the catalytic Zn(ii) ion resulting in enzyme inhibition. Adapting findings from the literature of Zn(ii) ion sensors, we previously reported chelating sulfonamide inh
INHIBITORS OF CATECHOL O-METHYL TRANSFERASE AND THEIR USE IN THE TREATMENT OF PSYCHOTIC DISORDERS
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Page/Page column 137, (2011/10/03)
The present invention relates to 4-pyridinone compounds which are inhibitors of catechol O-methyltransferase (COMT), and are useful in the treatment and prevention of neurological and psychiatric disorders and diseases in which COMT enzyme is involved. The present invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which COMT is involved
Compositions for dyeing keratinous fiber
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, (2008/06/13)
A composition for dyeing keratinous fiber which includes incorporated therein an oxidative color-developing substance, an enzyme which reacts with oxygen as a substrate but does not evolve hydrogen peroxide, and a weak reducing agent.