438037-25-3Relevant articles and documents
Mimicry of annonaceous acetogenins: enantioselective synthesis of a (4R)-hydroxy analogue having potent antitumor activity.
Jiang, Sheng,Liu, Zhong-Hai,Sheng, Gang,Zeng, Bu-Bing,Cheng, Xiao-Guang,Wu, Yu-Lin,Yao, Zhu-Jun
, p. 3404 - 3408 (2002)
The (4R)-hydroxylated analogues of annonaceous acetogenin mimicking compound 2 were designed and synthesized structurally on the basis of the naturally occurring annonaceous acetogenin bullatacin, which was discovered as a typical member of the novel fami
Enantiopure simple analogues of annonaceous acetogenins with remarkable selective cytotoxicity towards tumor cell lines
Zeng, Bu-Bing,Wu, Yikang,Yu, Qian,Wu, Yu-Lin,Li, Yan,Chen, Xiao-Guang
, p. 1934 - 1937 (2007/10/03)
Structure simplification with conservation of the essential functionalities for biological activity has been achieved with the design and synthesis of four analogues of annonaceous acetogenins. The compounds ((15 R/S, 24 R/S)-1) are easily synthesized wit