439-89-4

Basic information

• Product Name: Gentiannine
• Synonyms: Gentiannine;3,4-Dihydro-5-vinyl-1H-pyrano[3,4-c]pyridin-1-one;C06525;5-Ethenyl-3,4-dihydro-1H-pyrano[3,4-c]pyridin-1-one;5-Vinyl-3,4-dihydropyrano[3,4-c]pyridin-1-one
• CAS NO: 439-89-4
• Molecular Formula: C10H9NO2
• Molecular Weight: 175.184
• EINECS: 200-258-5
• Product Categories: Alkaloids
• Mol File: 439-89-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: 84-86℃
• Boiling Point: 386.5 °C at 760 mmHg
• Flash Point: 187.6 °C
• Appearance: /
• Density: 1.225
• Vapor Pressure: 3.52E-06mmHg at 25°C
• Refractive Index: 1.604
• PKA: 3.62±0.20(Predicted)
• CAS DataBase Reference: Gentiannine(CAS DataBase Reference)
• NIST Chemistry Reference: Gentiannine(439-89-4)
• EPA Substance Registry System: Gentiannine(439-89-4)

Safety Data

• Hazardous Substances Data: 439-89-4(Hazardous Substances Data)

Usage

Uses

Gentianine is used as an anti-inflammatory reducing the production of pro-inflammatory cytokines.

InChI:InChI=1/C10H9NO2/c1-2-7-5-11-6-9-8(7)3-4-13-10(9)12/h2,5-6H,1,3-4H2

Upstream product

• 57110-41-5 1-oxo-5-vinyl-1H-pyrano[3,4-c]pyridine-3-carboxylic acid ethyl ester 
• 57110-40-4 5-ethenyl-4-methyl-3-pyridinecarbonitrile 
• 50-00-0 formaldehyd 
• 99357-78-5 4-methyl-5-vinylnicotinic acid 

Relevant articles and documents

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NOVEL PYRIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

This invention relates to novel pyridine derivatives having an inhibitory effect on production of cytokines, which are involved in inflammatory responses, thus suggesting its usefulness as therapeutic agents for treating diseases related to inflammation, immune, chronic inflammation as well as an agent having an anti-inflammatory and analgesic effect. Further, this invention relates to a method of manufacturing the same and a pharmaceutical composition containing the same.