440648-53-3

Basic information

• Product Name: 4-((N-(4-fluorobenzyl)-4-methylphenylsulfonamido)methyl)-cyclohexanecarboxylic acid
• CAS NO: 440648-53-3
• Molecular Weight: 419.517
• Mol File: 440648-53-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-((N-(4-fluorobenzyl)-4-methylphenylsulfonamido)methyl)-cyclohexanecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-((N-(4-fluorobenzyl)-4-methylphenylsulfonamido)methyl)-cyclohexanecarboxylic acid(440648-53-3)
• EPA Substance Registry System: 4-((N-(4-fluorobenzyl)-4-methylphenylsulfonamido)methyl)-cyclohexanecarboxylic acid(440648-53-3)

Safety Data

• Hazardous Substances Data: 440648-53-3(Hazardous Substances Data)

Upstream product

• 1197-17-7 4-aminomethyl-cyclohexanecarboxylic acid 
• 98-59-9 p-toluenesulfonyl chloride 
• 459-46-1 4-Fluorobenzyl bromide 

Relevant articles and documents

Identification of human T2R receptors that respond to bitter compounds that elicit the bitter taste in compositions, and the use thereof in assays to identify compounds that inhibit (block) bitter taste in compositions and use thereof

The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds present in, e.g., coffee. Also, the invention relates to the discovery of specific compounds and compositions containing that function as bitter taste blockers and the use thereof as bitter taste blockers or flavor modulators in, e.g., coffee and coffee flavored foods, beverages and medicaments. Also, the present invention relates to the discovery of a compound that antagonizes numerous different human T2Rs and the use thereof in assays and as a bitter taste blocker in compositions for ingestion by humans and animals.