4442-54-0

Basic information

• Product Name: 1,4-Benzodioxane-6-carboxylic acid
• Synonyms: 1,4-Benzodioxane-6-;1,4-Benzodioxane-6-carboxylic acid 97%;2,3-dihydro-1,4-benzodioxin-6-carboxylic acid;RARECHEM AL BO 1905;TIMTEC-BB SBB007047;2,3-DIHYDRO-1,4-BENZODIOXINE-6-CARBOXYLIC ACID;2,3-DIHYDROBENZO[B][1,4]DIOXINE-6-CARBOXYLIC ACID;2,3-DIHYDRO-BENZO[1,4]DIOXINE-6-CARBOXYLIC ACID
• CAS NO: 4442-54-0
• Molecular Formula: C₉H₈O₄
• Molecular Weight: 180.16
• Product Categories: Benzodiozoles, Benzodioxines & Benzodioxepines;Carboxylic Acids;Benzodiozoles, Benzodioxines & Benzodioxepines;Carboxylic Acids;Benzodioxanes;Building Blocks;Heterocyclic Building Blocks;Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks
• Mol File: 4442-54-0.mol
• Article Data: 15

Chemical Properties

• Melting Point: 134-138 °C(lit.)
• Boiling Point: 339.781 °C at 760 mmHg
• Flash Point: 141.994 °C
• Appearance: Pale brown/Crystalline Solid
• Density: 1.377 g/cm³
• Vapor Pressure: 3.48E-05mmHg at 25°C
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)
• PKA: 4.37±0.20(Predicted)
• CAS DataBase Reference: 1,4-Benzodioxane-6-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Benzodioxane-6-carboxylic acid(4442-54-0)
• EPA Substance Registry System: 1,4-Benzodioxane-6-carboxylic acid(4442-54-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 4442-54-0(Hazardous Substances Data)

Usage

Chemical Properties

White to Off-White Solid

Uses

Different sources of media describe the Uses of 4442-54-0 differently. You can refer to the following data:
1. 1,4-Benzodioxane-6-carboxylic Acid is used in the preparation of new anti-inflammatory compounds containing the 1,4-benzodioxine system.
2. 3,4-Ethylenedioxybenzoic Acid is used in the preparation of new anti-inflammatory compounds containing the 1,4-benzodioxine system.

InChI:InChI=1/C9H8O4/c10-9(11)6-1-2-7-8(5-6)13-4-3-12-7/h1-2,5H,3-4H2,(H,10,11)/p-1

Upstream product

• 493-09-4 benzo-1,4-dioxane 
• 124-38-9 carbon dioxide 
• 67200-27-5 6-vinyl-2,3-dihydrobenzo[b][1,4]dioxine 
• 139-85-5 3,4-dihydroxybenzaldehyde 
• 39270-39-8 (2,3-dihydro-benzo[1,4]dioxin-6-yl)-methanol 
• 1370460-20-0 C₁₉H₁₉NO₃ 
• 20197-75-5 2,3-dihydro-benzo[1,4]dioxine-6-carboxylic acid methyl ester 
• 99-50-3 3,4-Dihydroxybenzoic acid 
• 590-29-4 potassium formate 
• 52287-51-1 6-bromo-1,4-benzodioxane 
• 57744-67-9 6-iodo-1,4-benzodioxane 
• 109-77-3 malononitrile 
• 77-95-2 1,3,4,5-tetrahydroxy-cyclohexanecarboxylic acid 
• 29668-44-8 2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde 

Downstream Products

• 57672-33-0 4,5-(ethylenedioxy)-2-nitrobenzoic acid 
• 143809-21-6 5-methyl-2,3-dihydrobenzo[b][1,4]dioxine-6-carboxylic acid 
• 959698-04-5 2-(benzylthio)-5-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1,3,4-oxadiazole 
• 1344999-25-2 2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-(3-methylbenzylthio)-1,3,4-oxadiazole 
• 1344999-26-3 2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-(4-nitrobenzylthio)-1,3,4-oxadiazole 
• 1344999-27-4 2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-(2-fluorobenzylthio)-1,3,4-oxadiazole 
• 1344999-28-5 2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-(2-nitrobenzylthio)-1,3,4-oxadiazole 
• 1344999-29-6 2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-(4-methylbenzylthio)-1,3,4-oxadiazole 
• 1344999-31-0 2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-(4-fluorobenzylthio)-1,3,4-oxadiazole 
• 1344999-32-1 2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-(3-nitrobenzylthio)-1,3,4-oxadiazole 
• 1344999-33-2 2-(4-chlorobenzylthio)-5-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1,3,4-oxadiazole 
• 1344999-34-3 2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-(4-iodobenzylthio)-1,3,4-oxadiazole 
• 1344999-35-4 2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-(2-methylbenzylthio)-1,3,4-oxadiazole 
• 1344999-36-5 2-(2-bromobenzylthio)-5-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1,3,4-oxadiazole 

Relevant articles and documents

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Bis(methoxypropyl) ether-promoted oxidation of aromatic alcohols into aromatic carboxylic acids and aromatic ketones with O2 under metal- and base-free conditions

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