4445-34-5

Basic information

• Product Name: Dibenz(c,e)oxepine-5(7H)-one
• Synonyms: Dibenz(c,e)oxepine-5(7H)-one;Diphenide;Dibenz[c,e]oxepin-5(7H)-one
• CAS NO: 4445-34-5
• Molecular Formula: C₁₄H₁₀O₂
• Molecular Weight: 210.228
• Mol File: 4445-34-5.mol
• Article Data: 37

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Dibenz(c,e)oxepine-5(7H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: Dibenz(c,e)oxepine-5(7H)-one(4445-34-5)
• EPA Substance Registry System: Dibenz(c,e)oxepine-5(7H)-one(4445-34-5)

Safety Data

• Hazardous Substances Data: 4445-34-5(Hazardous Substances Data)

Upstream product

• 6050-13-1 biphenyl-2,2'-dicarboxylic acid anhydride 
• 3594-90-9 2,2'-bis(hydroxymethyl)biphenyl 
• 40138-16-7 2-formylbenzene boronic acid 
• 6630-33-7 ortho-bromobenzaldehyde 
• 65-85-0 benzoic acid 
• 5807-64-7 diphenic acid dimethyl ester 
• 13404-97-2 2'-(bromomethyl)<1,1'-biphenyl>-2-carboxaldehyde 
• 1136-22-7 5,7-dihydrodibenzo[c,e]oxepine 
• 5159-41-1 2-iodobenzyl alcohol 
• 26638-43-7 2-methoxycarbonylbenzenesulfonyl chloride 
• 120-51-4 benzoic acid benzyl ester 
• 192637-89-1 2'-bromomethyl-biphenyl-2-carboxylic acid ethyl ester 
• 192637-88-0 2'-methylbiphenyl-2-carboxylic acid ethyl ester 
• 6091-64-1 2-bromobenzoic acid ethyl ester 

Downstream Products

• 119297-30-2 2'-(phthalimidomethyl)biphenyl-2-carboxylic acid 
• 125090-32-6 2-phthalimidomethyl-2'-carboxymethylbiphenyl-AlaOMe 
• 125090-31-5 2-phthalimidomethyl-2'-carboxymethylbiphenyl 
• 125127-50-6 2'-(1,3-Dioxo-1,3-dihydro-isoindol-2-ylmethyl)-biphenyl-2-carbonyl chloride 

Relevant articles and documents

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(Cyclopentadienone)iron-Catalyzed Transfer Dehydrogenation of Symmetrical and Unsymmetrical Diols to Lactones

Air-stable iron carbonyl compounds bearing cyclopentadienone ligands with varying substitution were explored as catalysts in dehydrogenative diol lactonization reactions using acetone as both the solvent and hydrogen acceptor. Two catalysts with trimethylsilyl groups in the 2- A nd 5-positions, [2,5-(SiMe3)2-3,4-(CH2)4(δ4-C4C= O)]Fe(CO)3 (1) and [2,5-(SiMe3)2-3,4-(CH2)3(δ4-C4C= O)]Fe(CO)3 (2), were found to be the most active, with 2 being the most selective in the lactonization of diols containing both primary and secondary alcohols. Lactones containing five-, six-, and seven-membered rings were successfully synthesized, and no over-oxidations to carboxylic acids were detected. The lactonization of unsymmetrical diols containing two primary alcohols occurred with catalyst 1, but selectivity was low based on alcohol electronics and modest based on alcohol sterics. Evidence for a transfer dehydrogenation mechanism was found, and insight into the origin of selectivity in the lactonization of 1°/2° diols was obtained. Additionally, spectroscopic evidence for a trimethylamine-ligated iron species formed in solution during the reaction was discovered.

Platinum-on-Carbon-Catalyzed Aqueous Oxidative Lactonization of Diols by Using Molecular Oxygen

A lactonization of various diols catalyzed by platinum on carbon (Pt/C) in water under an atmosphere of molecular oxygen was developed. Derivatives of 1,4- 1,5- and 1,6-diols were transformed into the corresponding five-, six-, and seven-membered lactones by the present oxidative lactonization method.