444911-56-2Relevant articles and documents
Manganese dioxide oxidation of hydroxylamines to nitrones
Cicchi, Stefano,Marradi, Marco,Goti, Andrea,Brandi, Alberto
, p. 6503 - 6505 (2001)
Several structurally differentiated N,N-dialkylhydroxylamines were oxidised to the corresponding nitrones using MnO2. Manganese dioxide revealed an efficient and mild reagent for oxidation of hydroxylamines, showing a level of regioselectivity
Practical synthesis of N-alkyl-N-glycosylhydroxylamines, multitalented precursors of enantiomerically pure nitrones
Cicchi, Stefano,Corsi, Massimo,Marradi, Marco,Goti, Andrea
, p. 2741 - 2743 (2007/10/03)
A practical synthesis of N-benzyl-N-glycosylhydroxylamines 3 (R=CH2Ph) is reported. The ability of these compounds to act as versatile synthetic intermediates is demonstrated by their oxidation followed by cycloaddition to N-glycosyl isoxazolidines and by the novel direct cycloaddition as masked acyclic, highly functionalized chiral nitrones.