444911-54-0

Basic information

• Product Name: (3aR,4R,6aR)-N-benzyl-tetrahydro-N-hydroxy-2,2-dimethylfuro[3,4-d]-1,3-dioxol-4-amine
• Synonyms: (3aR,4R,6aR)-N-benzyl-tetrahydro-N-hydroxy-2,2-dimethylfuro[3,4-d]-1,3-dioxol-4-amine
• CAS NO: 444911-54-0
• Molecular Weight: 265.309
• Mol File: 444911-54-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (3aR,4R,6aR)-N-benzyl-tetrahydro-N-hydroxy-2,2-dimethylfuro[3,4-d]-1,3-dioxol-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (3aR,4R,6aR)-N-benzyl-tetrahydro-N-hydroxy-2,2-dimethylfuro[3,4-d]-1,3-dioxol-4-amine(444911-54-0)
• EPA Substance Registry System: (3aR,4R,6aR)-N-benzyl-tetrahydro-N-hydroxy-2,2-dimethylfuro[3,4-d]-1,3-dioxol-4-amine(444911-54-0)

Safety Data

• Hazardous Substances Data: 444911-54-0(Hazardous Substances Data)

Upstream product

• 189996-60-9 2,3-O-isopropylidene-D-erythrose 
• 622-30-0 N-benzyl hydroxylalmine 
• 29601-98-7 N-benzylhydroxylamine hydrochloride 

Downstream Products

• 595559-81-2 (2R,3S,4R)-4-N-benzylhydroxylamino-2,3-O-isopropylidene-4-(2-thiazolyl)-1,2,3-butanetriol 
• 595559-94-7 (2R,3S,4R)-4-benzylamino-2,3-O-isopropylidene-4-(2-thiazolyl)-1,2,3-butanetriol 
• 595559-96-9 (2R,3S,4S)-4-benzylamino-2,3-O-isopropylidene-5-vinyl-1,2,3-pentanetriol 
• 643013-28-9 dimethyl (3R,4S,5R)-2-[(3aR,4R,6aR)-tetrahydro-2,2-dimethyl-3-phenylfuro[3,4-d][1,3]dioxol-4-yl]isoxazolidine-4,5-dicarboxylate 
• 595559-83-4 (2R,3S,4S)-4-N-benzylhydroxylamino-2,3-O-isopropylidene-5-vinyl-1,2,3-pentanetriol 
• 444911-56-2 (3aR,4R,6aR)-tetrahydro-2,2-dimethyl-N-(phenylmethylene)furo[3,4-d]-1,3-dioxol-4-amine N-oxide 

Relevant articles and documents

Preparation of N-Glycosylhydroxylamines and Their Oxidation to Nitrones for the Enantioselective Synthesis of Isoxazolidines

N-benzyl- and N-methyl-N-glycosylhydroxylamines 3a-i were conveniently obtained by reaction of sugars with N-substituted hydroxylamines according to a novel procedure. Subsequent oxidation occurred at the alkyl group, selectively affording the correspondi

Practical synthesis of N-alkyl-N-glycosylhydroxylamines, multitalented precursors of enantiomerically pure nitrones

A practical synthesis of N-benzyl-N-glycosylhydroxylamines 3 (R=CH2Ph) is reported. The ability of these compounds to act as versatile synthetic intermediates is demonstrated by their oxidation followed by cycloaddition to N-glycosyl isoxazolidines and by the novel direct cycloaddition as masked acyclic, highly functionalized chiral nitrones.