445312-08-3

Basic information

• Product Name: Benzonitrile, 3-(chloromethyl)-4-(4-fluorobenzoyl)-
• CAS NO: 445312-08-3
• Molecular Formula: C15H9ClFNO
• Molecular Weight: 273.694
• Mol File: 445312-08-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzonitrile, 3-(chloromethyl)-4-(4-fluorobenzoyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 3-(chloromethyl)-4-(4-fluorobenzoyl)-(445312-08-3)
• EPA Substance Registry System: Benzonitrile, 3-(chloromethyl)-4-(4-fluorobenzoyl)-(445312-08-3)

Safety Data

• Hazardous Substances Data: 445312-08-3(Hazardous Substances Data)

Upstream product

• 445312-07-2 2-chloromethyl-4-cyano-benzoyl chloride 
• 352-13-6 4-flourophenylmagnesium bromide 

Downstream Products

• 59729-33-8 1-(3-dimethylamino-propyl)-1-(4-fluoro-phenyl)-1,3-dihydro-isobenzofuran-5-carbonitrile 
• 64169-67-1 1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile 

Relevant articles and documents

Process for the preparation of 1-(3-dimethylaminopropyl)-1-(4-Fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile

Method for the preparation of 1-(3-dimethylaminopropyl)-1-(4-fluoro-phenyl)-1,3-dihydroisobenzofuran-5-carbonitrile (citalopram) comprising the reaction of a compound of formula wherein X is a halogen, with organometallic dimethylaminopropyl halide. Other aspects of the invention are new compounds of formula II and formula III and their preparation.