445479-01-6

Basic information

• Product Name: Carbamic acid, [(1S,2R)-2-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI)
• Synonyms: Carbamic acid, [(1S,2R)-2-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI);tert-butyl (1S,2R)-2-aMinocyclopentylcarbaMate;tert-butyl N-[(1S,2R)-2-aMinocyclopentyl]carbaMate;(1S,2R)-2-AMino-1-(Boc-aMino)cyclopentane;((1S,2R)-2-Aminocyclopentyl)carbamic acid tert-butyl ester;(1S,2R)-1-[N-(t-Butoxycarbonyl)amino]-2-cyclopentanamine;tert-Butyl N-((2R,1S)-2-aminocyclopentyl)carbamate;(1R,2S)-2-(Boc-amino)cyclopentylamine
• CAS NO: 445479-01-6
• Molecular Formula: C₁₀H₂₀N₂O₂
• Molecular Weight: 200.278
• Product Categories: N-BOC;CYCLOPENTANE
• Mol File: 445479-01-6.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 304.2±31.0 °C(Predicted)
• Appearance: /
• Density: 1.04±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 12.25±0.40(Predicted)
• CAS DataBase Reference: Carbamic acid, [(1S,2R)-2-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(1S,2R)-2-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI)(445479-01-6)
• EPA Substance Registry System: Carbamic acid, [(1S,2R)-2-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI)(445479-01-6)

Safety Data

• Hazard Codes: Xi
• Statements: 38-41
• Safety Statements: 26-39
• WGK Germany: 3
• Hazardous Substances Data: 445479-01-6(Hazardous Substances Data)

Usage

General Description

Carbamic acid, [(1S,2R)-2-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI) is a chemical compound with a molecular formula of C10H19NO2. It is also known by its IUPAC name as tert-butyl (1S,2R)-2-aminocyclopentylcarbamate. Carbamic acid, [(1S,2R)-2-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI) is a tert-butyl ester derivative of [(1S,2R)-2-aminocyclopentyl]carbamic acid and is commonly used in the synthesis of pharmaceutical drugs and research purposes. It is a white, crystalline solid and is considered to be a potentially hazardous chemical, requiring proper handling and storage to prevent any adverse effects on human health and the environment.

Upstream product

• 365996-19-6 tert-butyl (+/-)-cis-(2-aminocyclopentyl)carbamate 
• 141-78-6 ethyl acetate 
• 93-92-5 1-phenylethyl acetate 
• 721395-14-8 (1S,2R)-2-(N-tert-butoxycarbonylamino)-1-azidocyclopentane 
• 58632-95-4 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile 
• 930-45-0 (1S,2S)-2-aminocyclopentanol 
• 125356-51-6 (1S,2S)-trans-2-azidocyclopentanol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 756874-86-9 (1S,2S)-2-azido-cyclopentyl butyrate 
• 630386-07-1 (1S,2S)-2-(tert-butoxycarbonylamino)cyclopentyl methanesulfonate 
• 181657-56-7 (1S,2S)-2-(benzyloxy)cyclopentanamine 
• 145106-43-0 (1S,2S)-trans-2-(tert-butoxycarbonylamino)cyclopentanol 
• 445479-00-5 (1S, 2S)-2-benzyloxy-cyclopentyl-carbamic acid tert-butyl ester 
• 756874-87-0 (1R,2S)-2-(N-tert-butoxycarbonylamino)-1-azidocyclopentane 

Relevant articles and documents

CAFFEINE INHIBITORS OF MTHFD2 AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

SAR and X-ray structures of enantiopure 1,2-cis-(1R,2S)-cyclopentyldiamine and cyclohexyldiamine derivatives as inhibitors of coagulation Factor Xa

In the search of Factor Xa (FXa) inhibitors structurally different from the pyrazole-based series, we identified a viable series of enantiopure cis-(1R,2S)-cycloalkyldiamine derivatives as potent and selective inhibitors of FXa. Among them, cyclohexyldiam

cis-Cyclopentyl PNA (cpPNA) as constrained chiral PNA analogues: stereochemical dependence of DNA/RNA hybridization.

DNA/RNA hybridization studies of PNA-T oligomers with cis-(1S,2R/1R,2S)-cyclopentyl units in the backbone show stereochemistry dependent binding with RNA/DNA discrimination.