4704-76-1

Basic information

• Product Name: 4-(benzyloxymethyl)-1,3-dioxo-2-thiolane 2-oxide
• Synonyms: 4-(benzyloxymethyl)-1,3-dioxo-2-thiolane 2-oxide
• CAS NO: 4704-76-1
• Molecular Weight: 228.269
• Mol File: 4704-76-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-(benzyloxymethyl)-1,3-dioxo-2-thiolane 2-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(benzyloxymethyl)-1,3-dioxo-2-thiolane 2-oxide(4704-76-1)
• EPA Substance Registry System: 4-(benzyloxymethyl)-1,3-dioxo-2-thiolane 2-oxide(4704-76-1)

Safety Data

• Hazardous Substances Data: 4704-76-1(Hazardous Substances Data)

Upstream product

• 14593-43-2 benzyl allyl ether 
• 15028-56-5 4-(benzyloxymethyl)-2,2-dimethyl-1,3-dioxolane 
• 13071-59-5 3-benzyloxypropan-1,2-diol 

Downstream Products

• 93950-95-9 1-benzyloxy-2-carbamoyloxy-3-(2-methoxy-phenoxy)-propane 
• 176094-67-0 4-benzyloxy-1,1-dibromo-3-hydroxy-butane 
• 176094-54-5 (S)-4-(Benzyloxymethyl)-2,2-dioxo-1,3,2-dioxathiolane 
• 93728-27-9 1-benzyloxy-3-(2-methoxy-phenoxy)-propan-2-ol 
• 13071-59-5 3-benzyloxypropan-1,2-diol 
• 63473-97-2 2-hydroxy-3-benzyloxy-N-benzyl-1-propanamine 
• 19343-24-9 F₀₀₅₀-0006 
• 99805-19-3 (R,S)-1-azido-3-benzyloxy-2-propanol 
• 150855-02-0 1-Benzyloxy-3-(naphthalen-1-yloxy)-propan-2-ol 
• 6972-79-8 dibenzyl glycerol 
• 99789-33-0 1-Benzyloxy-3-phenylthio-2-propanol 
• 50610-95-2 1-benzyloxy-2-hydroxy-3-phenoxypropane 
• 137618-52-1 4-(benzyloxy)-3-hydroxybutanenitrile 

Relevant articles and documents

Chemo- and Regioselective Functionalization of Polyols through Catalytic C(sp3)-C(sp3) Kumada-Type Coupling of Cyclic Sulfate Esters

This contribution describes a copper-catalyzed, C(sp3)-C(sp3) cross-coupling reaction of cyclic sulfate esters, a distinct class of electrophilic derivatives of polyols, with alkyl Grignard reagents to afford functionalized alcohol products in good yields. The method is operationally simple and highlights the potential of cyclic sulfate esters as highly reactive substrates in catalytic, chemoselective polyol transformations.

Nucleophilic Addition to Cyclic 1,2-Sulfites

Addition of heteroatom nucleophiles has been shown to attack at either the C5- or the S-atom sites in 4-(benzyloxymethyl)-1,3-dioxa-2-thiolane 2-oxide.No C4-reactivity was observed.The regioselectivity depended on the type of nucleophile.