471905-62-1

Basic information

• Product Name: 4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohex-1-en-1-yl trifluoromethanesulfonate
• Synonyms: 4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohex-1-en-1-yl trifluoromethanesulfonate
• CAS NO: 471905-62-1
• Molecular Weight: 516.894
• Mol File: 471905-62-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohex-1-en-1-yl trifluoromethanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohex-1-en-1-yl trifluoromethanesulfonate(471905-62-1)
• EPA Substance Registry System: 4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohex-1-en-1-yl trifluoromethanesulfonate(471905-62-1)

Safety Data

• Hazardous Substances Data: 471905-62-1(Hazardous Substances Data)

Upstream product

• 471903-20-5 4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanone 
• 145100-51-2 N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulphonyl]methanesulphonamide 
• 85117-99-3 2-(bromomethyl)-1,4-difluorobenzene 
• 106-54-7 p-Chlorothiophenol 
• 471905-61-0 2-[1-[(4-chlorophenyl)sulfonyl]ethenyl]-1,4-difluorobenzene 
• 470716-51-9 2-[[(4-chlorophenyl)sulfonyl]methyl]-1,4-difluorobenzene 
• 470716-52-0 2-[[(4-chlorophenyl)thio]methyl]-1,4-difluorobenzene 

Downstream Products

• 471905-41-6 3-((1S,4R)-4-((4-chlorophenyl)sulfonyl)-4-(2,5- difluorophenyl)cyclohexyl)propanoic acid 
• 942296-40-4 3-[4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohex-1-enyl]propanoic acid 

Relevant articles and documents

A practical synthesis of a γ-secretase inhibitor

(Chemical Equation Presented) A practical and scaleable synthesis of the γ-secretase inhibitor 1 is reported. The inhibitor consists of a central trisubstituted cyclohexane core with appended propionic acid, 2,5-difluorophenyl, and 4-chlorophenylsulfonyl