4860-88-2

Basic information

• Product Name: 2-hydroxy-7-methyl-4H,5H-pyrano[4,3-b]pyran-4,5-dione
• CAS NO: 4860-88-2
• Molecular Formula: C₉H₆O₅
• Molecular Weight: 194.1409
• Mol File: 4860-88-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 466.5°C at 760 mmHg
• Flash Point: 198.2°C
• Density: 1.56g/cm³
• Vapor Pressure: 1.15E-10mmHg at 25°C
• Refractive Index: 1.623
• CAS DataBase Reference: 2-hydroxy-7-methyl-4H,5H-pyrano[4,3-b]pyran-4,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-7-methyl-4H,5H-pyrano[4,3-b]pyran-4,5-dione(4860-88-2)
• EPA Substance Registry System: 2-hydroxy-7-methyl-4H,5H-pyrano[4,3-b]pyran-4,5-dione(4860-88-2)

Safety Data

• Hazardous Substances Data: 4860-88-2(Hazardous Substances Data)

Usage

General Description

2-hydroxy-7-methyl-4H,5H-pyrano[4,3-b]pyran-4,5-dione is a chemical compound that belongs to the class of pyranopyran-4,5-dione derivatives. It is a heterocyclic organic compound containing a pyran ring fused to a pyranone ring, with a hydroxyl group and a methyl group attached to the pyran ring. 2-hydroxy-7-methyl-4H,5H-pyrano[4,3-b]pyran-4,5-dione has potential biological activities and is being studied for its potential therapeutic effects. It may have applications in the pharmaceutical industry and could be of interest to medicinal chemists and researchers studying drug discovery and development.

Upstream product

• 675-10-5 4-hydroxy-6-methyl-2-pyron 
• 1663-67-8 malonoyl dichloride 
• 29736-80-9 3,5-dioxohexanoic acid methyl ester 
• 33176-11-3 2,7-dimethyl-4H-pyrano<3,2-c>-2H-pyran-4,5-dione 
• 771-03-9 3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one 

Downstream Products

• 16929-94-5 Methyl 2,4,6-trihydroxy-3-acetylbenzoate 
• 57439-16-4 methyl 2-hydroxy-6-methoxy-4-methylbenzoate 
• 15346-85-7 Dimethyl 2,4-dihydroxy-6-methylbenzene-1,3-dicarboxylate 
• 771-03-9 3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one 
• 56364-25-1 4-hydroxy-6-methyl-3-[(2E)-3-phenylprop-2-enoyl]-2H-pyran-2-one 
• 1004-36-0 2,6-dimethylpyrone 
• 480-64-8 orsellinic acid 

Relevant articles and documents

Reactions of fused and unfused α-pyrones with magnesium alkoxide, sodium alkoxide and water as the nucleophile: effects of chelation

The reactions between a series of α-pyrones (two mono- and three fused) and the non-chelating base sodium alkoxide, the chelating base magnesium alkoxide and water as the nucleophile, have been studied.Aromatic and other products formed reflect the points of attack on the pyrone systems and when sodium methoxide is used the ensuing cyclisation is preferentially by aldol mechanisms.The employment of excess magnesium methoxide or ethoxide gives magnesium-chelated precursors and the nature of products now depends on these intermediates, and the protection afforded by such magnesium chelation to the reaction products.In the case of structures containing chelated β-keto ester features the chelates are screened from attack as aldol acceptors, but are effective Claisen acceptors.In such chelates an adjacent methylene is activated by further magnesium alkoxide to act as an aldol or Claisen donor.These contrasting aldol/Claisen reactivities, as between a non-chelating and a chelating base, are illustrated in the ensuing chemistry of the pyrones.Treatment with water releases the main carbon chain with decarboxylation, from which new products may form.