490-17-5 Usage
Description
From the leaves of Erythroxylon truxillense Rusby, Hesse isolated an amorphous
alkaloid which he designated Cocamine. This was subsequently shown by
Liebermann to be a mixture of two isomeric bases and, although the pure
alkaloids have not yet been obtained from the alkaloidal mixture owing to
difficulties in their separation, each has been prepared synthetically. This
particular alkaloid is an amorphous white powder which is soluble in all
organic solvents except light petroleum and also insoluble in H20. Solutions of
the base are alllaevorotatory and have an intensely bitter taste. Acid hydrolysis
with dilute HCl yields MeOH, (-)-ecgonine and Q-truxillic acid, m.p. 228°C. The
alkaloid is synthesized by the action of α-truxillic anhydride on (-)-ecgonine
followed by methylation of the resulting α-truxilloylecgonine.
References
Hesse., Pharm. Zeit., 407,668 (1887)
Liebermann., Ber., 21,2342 (1888)
Hesse., ibid, 22, 665 (1889)
Liebermann, Drory., ibid, 22,682 (1889)
Check Digit Verification of cas no
The CAS Registry Mumber 490-17-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,9 and 0 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 490-17:
(5*4)+(4*9)+(3*0)+(2*1)+(1*7)=65
65 % 10 = 5
So 490-17-5 is a valid CAS Registry Number.
InChI:InChI=1/C38H46N2O8/c1-39-23-15-17-25(39)31(35(41)45-3)27(19-23)47-37(43)33-29(21-11-7-5-8-12-21)34(30(33)22-13-9-6-10-14-22)38(44)48-28-20-24-16-18-26(40(24)2)32(28)36(42)46-4/h5-14,23-34H,15-20H2,1-4H3/t23-,24-,25+,26+,27-,28-,29?,30?,31+,32+,33?,34?/m0/s1
