49744-73-2

Basic information

• Product Name: CP 84
• CAS NO: 49744-73-2
• Molecular Weight: 201.225
• Mol File: 49744-73-2.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: CP 84(CAS DataBase Reference)
• NIST Chemistry Reference: CP 84(49744-73-2)
• EPA Substance Registry System: CP 84(49744-73-2)

Safety Data

• Hazardous Substances Data: 49744-73-2(Hazardous Substances Data)

Upstream product

• 61049-69-2 3-O-benzylmaltol 
• 62-53-3 aniline 
• 30724-94-8 3-(β-D-glucopyranosyloxy)-2-methyl-1-phenyl-4(1H)-pyridinone 
• 118-71-8 Maltol 
• 161175-83-3 3-Benzyloxy-2-methyl-1-phenyl-1H-pyridin-4-one 

Downstream Products

• 250638-51-8 [Rh(CO)2(C₆H₅NCHCHCOCOC(CH₃))] 
• 244229-52-5 cis-bis(3-hydroxy-2-methyl-1-phenyl-4-pyridinonato)dioxomolybdenum(VI) 
• 1589128-15-3 2-methyl-1-phenylpyridine-4-one-3-yladamantan-1-yl ethanoate 
• 54007-06-6 (3-hydroxy-2-methyl-1-phenyl-4(1H)-pyridinato)iron(III) 
• 250638-57-4 [Rh(C₈H₁₄)(CO)(C₆H₅NCHCHCOCOC(CH₃))] 
• 917890-00-7 tris(1-phenyl-2-methyl-3-hydroxy-4-pyridinonato)vanadium(IV)⁽¹⁺⁾ 
• 404959-66-6 3-hydroxy-2-methyl-1-phenyl-4(1H)-pyridinethione 

Relevant articles and documents

Design, synthesis and evaluation of 3-hydroxypyridin-4-ones as inhibitors of catechol-O-methyltransferase

Abstract: The most effective treatment of Parkinson’s disease is restoring central dopamine levels with levodopa, the metabolic precursor of dopamine. However, due to extensive peripheral metabolism by aromatic l-amino acid decarboxylase and catechol-O-me

Discovery of N-Aryl-pyridine-4-ones as Novel Potential Agrochemical Fungicides and Bactericides

A series of N-aryl-pyridine-4-one derivatives were designed and synthesized using maltol and antidesmone as lead compounds, and then their fungicidal/bactericidal activities and possible mechanism of action against Colletotrichum musae were explored. Most of these compounds exhibited significant fungicidal activity in vitro. Especially, compound 23 has more than 90% inhibitory activity against nine plant pathogenic fungi at 50 μg mL-1, which is superior to azoxystrobin. Moreover, an in vivo bioassay also demonstrated that compound 23 exhibited high-efficiency broad-spectrum antifungal activity and can effectively control postharvest diseases of mango. In addition, it was found that compounds 22 and 23 can also effectively control rice bacterial leaf blight in pot experiments, which was even more effective than zhongshengmycin. Preliminary mechanism studies revealed that compound 23 may cause cell membrane and mitochondria destruction. These findings indicate that compound 23 can be used to develop potential agrochemical fungicides and bactericides.

COMPOSITIONS AND METHODS FOR INHIBITING INFLUENZA RNA POLYMERASE PA ENDONUCLEASE

There are provided inter alia metalloenzyme inhibitors, such as inhibitors of influenza A RNA dependent RNA polymerase PA subunit endonuclease, and methods of synthesis and use of the same.