499195-60-7 Usage
General Description
Ethyl 4-(2-chloropyrimidin-4-yl)benzoate is a chemical compound with the molecular formula C15H12ClNO2. It is an ester derivative of 2-chloropyrimidine and benzoic acid, and it is commonly used in the pharmaceutical industry as an intermediate in the synthesis of various medications. ethyl 4-(2-chloropyrimidin-4-yl)benzoate has potential biological activities, including anti-inflammatory and anti-tumor properties, making it a valuable building block in drug discovery and development. Its unique structure and properties make it an important chemical in the field of medicinal chemistry and pharmaceutical research.
Check Digit Verification of cas no
The CAS Registry Mumber 499195-60-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,9,9,1,9 and 5 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 499195-60:
(8*4)+(7*9)+(6*9)+(5*1)+(4*9)+(3*5)+(2*6)+(1*0)=217
217 % 10 = 7
So 499195-60-7 is a valid CAS Registry Number.
499195-60-7Relevant articles and documents
N-CYANOMETHYLAMIDES AS INHIBITORS OF JANUS KINASE
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Page/Page column 17; 18, (2015/02/25)
The present invention relates to compounds of general formula (1) that are inhibitors of Janus Kinase (JAK), a family of tyrosine kinases that are involved in inflammatory conditions, autoimmune diseases, proliferative diseases, allergy, transplant reject
A novel and efficient synthesis of 4-phenyl-2-chloropyrimidines from acetophenone cyanoimines
Cuccia, Salvatore J.,Fleming, Linda B.,France, Donald J.,Wood, William W.
, p. 3011 - 3018 (2007/10/03)
A versatile and efficient 2 step synthesis of 4-phenyl-2-chloropyrimidines is described. The reaction proceeds by treatment of acetophenone cyanoimines under Vilsmeier-Haack conditions to give the target compounds in moderate yields.
