5027-77-0

Basic information

• Product Name: Ethyl pyrrolidin-2-yl-acetate
• Synonyms: Ethyl pyrrolidin-2-yl-acetate;2-Pyrrolidineacetic acid ethyl ester;Ethyl 2-(pyrrolidin-2-yl)acetate
• CAS NO: 5027-77-0
• Molecular Formula: C₈H₁₅NO₂
• Molecular Weight: 157.2102
• Product Categories: pharmacetical
• Mol File: 5027-77-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 210.9 °C at 760 mmHg
• Flash Point: 81.3 °C
• Appearance: /
• Density: 0.989 g/cm³
• Vapor Pressure: 0.188mmHg at 25°C
• Refractive Index: 1.443
• Storage Temp.: 2-8°C
• PKA: 10.07±0.10(Predicted)
• CAS DataBase Reference: Ethyl pyrrolidin-2-yl-acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl pyrrolidin-2-yl-acetate(5027-77-0)
• EPA Substance Registry System: Ethyl pyrrolidin-2-yl-acetate(5027-77-0)

Safety Data

• Hazardous Substances Data: 5027-77-0(Hazardous Substances Data)

Usage

General Description

Ethyl pyrrolidin-2-yl-acetate is a chemical compound commonly used in the fragrance and flavor industry. It is a colorless liquid with a sweet, floral odor, and is often found in perfumes, soaps, and detergents. This chemical is known for its ability to enhance and prolong the scent of various products. It is also used as a flavoring agent in food and beverages, adding a fruity and floral note to the final product. Additionally, Ethyl pyrrolidin-2-yl-acetate is used in the production of pharmaceuticals, specifically in the manufacturing of certain drugs and medications. Overall, this chemical is a versatile and important ingredient in various industries.

InChI:InChI=1/C8H15NO2/c1-2-11-8(10)6-7-4-3-5-9-7/h7,9H,2-6H2,1H3

Upstream product

• 1071-46-1 hydrogen ethyl malonate 
• 5981-17-9 dodecahydro-3a,6a,9a-triaza-trindene 
• 1008751-73-2 t-butyl (E)-5-(ethoxycarbonyl)pent-4-enylcarbamate 
• 4778-25-0 (1H-pyrrol-2-yl)acetic acid ethyl ester 

Downstream Products

• 78178-75-3 ethyl 1-<2-carbethoxy-2-(4'-benzyloxy-3'-methoxyphenyl)ethyl>pyrrolidinyl-2-acetate 
• 194154-91-1 (+/-)-1-(tert-Butoxycarbonyl)pyrrolidine-2-acetic acid 
• 136272-85-0 3-(1-pyrrolidinyl)-1-(3-trifluoromethylphenyl)-1,8-naphthyridin-2(1H)-one 
• 35620-60-1 1-carbethoxy-2,3-dioxopyrrolizidine 
• 118758-56-8 tert-butyl 2-(2-ethoxy-2-oxoethyl)pyrrolidine-1-carboxylate 

Relevant articles and documents

First synthesis of pyrrolo[1,2:1′,2′]azepino[5,6-b]indole derivatives

A new family of pyrrolo[1,2:1′,2′]azepino[5,6-b]indole derivatives 8,15 related to anthramycin skeleton was prepared in good yield from indole-2-carboxylic acid and β-aminoesters 4 through intramolecular cyclisation.

Angiotensin II antagonists

This invention provides novel heterocyclic derivatives, their pharmaceutical formulations, and their use for antagonizing angiotensin II receptors in mammals.

Decarboxylation Reaction. X. Introduction of a Carbon unit at the α-Position of Amines by Reaction of Hexahydro-1,3,5-triazines with Carboxylic Acids

An efficient method for introducing a carbon unit at the α-position of alicyclic amines is described.The method involves the reaction of monocyclic or tetracyclic hexahydro-1,3,5-triazines with trichloroacetic acid, cyanoacetic acid, malonic acid and their derivatives, which are introduced into the α-position of amines in the decarboxylated form.Keywords --- 1,3,5-trialkylhexahydro-1,3,5-triazine; trimer of alicyclic imine; decarboxylation; β-amino acid; carboxylic acid