50290-45-4

Basic information

• Product Name: 2-phenyl-10H-pyrimido<1,2-a>benzimidazol-4-one
• Synonyms: 2-phenyl-10H-pyrimido<1,2-a>benzimidazol-4-one
• CAS NO: 50290-45-4
• Molecular Weight: 261.283
• Mol File: 50290-45-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-phenyl-10H-pyrimido<1,2-a>benzimidazol-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-10H-pyrimido<1,2-a>benzimidazol-4-one(50290-45-4)
• EPA Substance Registry System: 2-phenyl-10H-pyrimido<1,2-a>benzimidazol-4-one(50290-45-4)

Safety Data

• Hazardous Substances Data: 50290-45-4(Hazardous Substances Data)

Upstream product

• 934-32-7 1H-benzimidazol-2-amine 
• 637-44-5 phenylpropyolic acid 
• 4891-38-7 phenylpropynoic acid methyl ester 
• 536-74-3 phenylacetylene 
• 420-04-2 CYANAMID 
• 898138-80-2 N-(2-bromophenyl)-3-phenylpropiolamide 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 3446-58-0 3-oxo-3-phenylpropanamide 

Downstream Products

• 1031620-28-6 2-(4-oxo-2-phenylpyrimido[1,2-a]benzimidazol-10(4H)-yl)-N-(3-methoxyphenyl)acetamide 
• 1215289-38-5 10-(4-methylbenzyl)-2-phenyl-4,10-dihydrobenzo[4,5]imidazo[1,2-a]pyrimidin-4-one 

Relevant articles and documents

Copper-Catalyzed Domino Synthesis of Benzo[4,5]imidazo[1,2-a]pyrimidin-4(10H)-ones using Cyanamide as a Building Block

An efficient and practical copper-catalyzed domino synthesis of benzo[4,5]imidazo[1,2-a]pyrimidin-4(10H)-ones has been developed. The protocol uses N-(2-halophenyl)-3-alkylpropiolamides and cyanamide as the starting materials, inexpensive copper(I) iodide and pipecolinic acid as the catalyst and ligand, and the corresponding products were obtained in moderate to good yields.

Generation of 500-member library of 10-alkyl-2-R1,3-R 2-4,10-dihydrobenzo[4,5]imidazo[1,2-a]pyrimidin-4-ones

Representative benzimidazopyrimidinones were previously reported to be intercalating antitumor agents. In this work, we used 2-substituted 4,10-dihydrobenzo [4,5]imidazo[1,2-a]pyriminin-4-ones for their diversification by regioselective alkylation. Under

Studies on heterocyclic compounds. XIII. Reaction of 2 aminobenzazoles with acetylenic compounds

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