51954-54-2

Basic information

• Product Name: 2-(p-tolylthio)pyridine
• Synonyms: 2-(p-tolylthio)pyridine
• CAS NO: 51954-54-2
• Molecular Weight: 201.292
• Mol File: 51954-54-2.mol
• Article Data: 32

Chemical Properties

• CAS DataBase Reference: 2-(p-tolylthio)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(p-tolylthio)pyridine(51954-54-2)
• EPA Substance Registry System: 2-(p-tolylthio)pyridine(51954-54-2)

Safety Data

• Hazardous Substances Data: 51954-54-2(Hazardous Substances Data)

Upstream product

• 5029-67-4 2-iodopyridine 
• 106-45-6 para-thiocresol 
• 2637-34-5 2-Sulfanylpyridine 
• 2127-03-9 2,2'-dipyridyldisulphide 
• 624-31-7 4-tolyl iodide 
• 109-04-6 2-bromo-pyridine 
• 142-08-5 2-hydroxypyridin 
• 5720-05-8 4-methylphenylboronic acid 
• 65007-00-3 pyridin-2-yl trifluoromethanesulfonate 
• 57785-86-1 pyridin-2-yl tosylate 
• 3847-19-6 2-acetoxypyridine 
• 197958-29-5 pyridin-2-ylboronic acid 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 372-48-5 2-fluoropyridine 

Downstream Products

• 4783-68-0 2-phenoxypyridine 
• 106-45-6 para-thiocresol 
• 1370652-74-6 1,2-bis(5-methylbiphenyl-2-yl)disulfane 
• 643-93-6 3-methylbiphenyl 
• 52258-16-9 4-methylphenyl 2-naphthyl sulfide 
• 381725-49-1 2-methoxy-5-(pyridin-2-yl)pyridine 
• 56100-22-2 6-methyl-2,2'-bipyridine 
• 205052-93-3 6-bromo-4-methoxy-2,2'-bipyridine 
• 10273-88-8 3-methyl-2,2'-bipyridine 
• 366-18-7 [2,2]bipyridinyl 
• 581-50-0 2,3'-bipyridine 
• 1008-89-5 2-phenylpyridine 
• 1289560-30-0 2-{4-methyl-2-[(E)-styryl]phenylsulfinyl}pyridine 
• 1289560-29-7 (E)-butyl 3-(5-methyl-2-(pyridin-2-ylsulfinyl)phenyl)acrylate 

Relevant articles and documents

Convenient MW-assisted synthesis of unsymmetrical sulfides using sulfonyl hydrazides as aryl thiol surrogate

An efficient synthesis of unsymmetrical sulfides has been achieved via the cross-coupling reaction of aryl/het-aryl/benzyl halides with stable and easily workable sulfonyl hydrazides as thiol substitutes by means of [DBU][HOAc] and CuI under microwave irr

Dimsyl Anion Enables Visible-Light-Promoted Charge Transfer in Cross-Coupling Reactions of Aryl Halides

A methodology is reported for visible-light-promoted synthesis of unsymmetrical chalcogenides enabled by dimsyl anion in the absence of transition-metals or photoredox catalysts. The cross-coupling reaction between aryl halides and diaryl dichalcogenides proceeds with electron-rich, electron-poor, and heteroaromatic moieties. Mechanistic investigations using UV-Vis spectroscopy, time-dependent density functional theory (TD-DFT) calculations, and control reactions suggest that dimsyl anion forms an electron-donor-acceptor (EDA) complex capable of absorbing blue light, leading to a charge transfer responsible for generation of aryl radicals from aryl halides. This previously unreported mechanistic pathway may be applied to other light-induced transformations performed in DMSO in the presence of bases and aryl halides.

Modulation of photochemical oxidation of thioethers to sulfoxides or sulfones using an aromatic ketone as the photocatalyst

We have developed an eco-friendly and chemo-selective photocatalytic synthesis of sulfoxides or sulfones via oxidation of sulfides (thioethers) at ambient temperature using air or O2 as the oxidant. An inexpensive thioxanthone was used as the photocatalyst. Our method offers excellent chemical yields and good functional group tolerance. The hydrogen bonding between hexafluoro-2-propanol (HFIP) and sulfoxides may play an important role in minimizing the over-oxidization of sulfoxides.