52374-26-2Relevant articles and documents
Silver-catalyzed intermolecular amination of C-H groups
Li, Zigang,Capretto,Rahaman,He, Chuan
, p. 5184 - 5186 (2007)
(Chemical Equation Presented) Teamwork: The dinuclear silver complex [Ag2(OTf)2(bp)2] (OTf = trifluoromethane- sulfonate, bp = bathophenanthroline) catalyzes the intermolecular amination of saturated C-H bonds by using Phl=NNs (Ns = p-nitrosulfonyl) as the nitrene precursor (see scheme). Preliminary investigations suggest that the dinuclear structural motif is crucial to catalytic performance.
Metal-Free β-Amino Alcohol Synthesis: A Two-step Smiles Rearrangement
Yang, Di,Xie, Cai-Xia,Wu, Xiao-Tian,Fei, Luo-Ran,Feng, Lei,Ma, Chen
supporting information, p. 14905 - 14915 (2020/11/13)
A novel method for the synthesis of β-amino alcohols has been demonstrated under mild reaction conditions with a broad scope via a two-step Smiles rearrangement. What is more, theoretical calculations have been performed to confirm the rationality of the mechanism. The method has been proved to be notably effective for N-arylated amino alcohols, which are difficult to synthesize by traditional methods.
Palladium-Catalyzed Enantioselective 1,1-Fluoroarylation of Aminoalkenes
He, Ying,Yang, Zhenyu,Thornbury, Richard T.,Toste, F. Dean
supporting information, p. 12207 - 12210 (2015/10/12)
The development of an enantioselective palladium-catalyzed 1,1-fluoroarylation of unactivated aminoalkenes is described. The reaction uses arylboronic acids as the arene source and Selectfluor as the fluorine source to generate benzylic fluorides in good yields with excellent enantioselectivities. This transformation, likely proceeding through an oxidative Heck mechanism, affords 1,1-difunctionalized alkene products.
