54769-58-3

Basic information

• Product Name: 1H-benzo[d][1,2,3]triazol-1-yl 4-nitrobenzenesulfonate
• Synonyms: 1H-benzo[d][1,2,3]triazol-1-yl 4-nitrobenzenesulfonate
• CAS NO: 54769-58-3
• Molecular Weight: 320.285
• Mol File: 54769-58-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1H-benzo[d][1,2,3]triazol-1-yl 4-nitrobenzenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-benzo[d][1,2,3]triazol-1-yl 4-nitrobenzenesulfonate(54769-58-3)
• EPA Substance Registry System: 1H-benzo[d][1,2,3]triazol-1-yl 4-nitrobenzenesulfonate(54769-58-3)

Safety Data

• Hazardous Substances Data: 54769-58-3(Hazardous Substances Data)

Upstream product

• 2592-95-2 benzotriazol-1-ol 
• 98-74-8 4-Nitrobenzenesulfonyl chloride 

Downstream Products

• 164861-48-7 Z-L-Phe-L-Val-L-Pro-NH₂ 
• 1566605-91-1 1-methoxycarbonylmethyl-1-(4-nitrobenzenesulfonyl)-4,4-bis(tert-butoxycarbonylmethyl)-1,4-diazabutane 
• 154561-22-5 Z-Aib-OBt 
• 52374-26-2 N-cyclohexyl-p-nitrobenzenesulfonamide 
• 1396967-04-6 methyl 2-(4-nitrophenylsulfonamido)propanoate 

Relevant articles and documents

Controlling multivalency and multimodality: Up to pentamodal dendritic platforms based on diethylenetriaminepentaacetic acid cores

A highly versatile synthetic strategy is described to generate multimodal and multivalent platforms based on a diethylenetriaminepentaacetic (DTPA) core. Compounds with different functionalization patterns, from mono- to pentamodal, have been prepared using robust and simple chemistry.

Sulfonamide synthesis using N-hydroxybenzotriazole sulfonate: An alternative to pentafluorophenyl (PFP) and trichlorophenyl (TCP) esters of sulfonic acids

The N-hydroxybenzotriazole (HOBt) sulfonate esters undergo amidation under ambient conditions in the presence of di-isopropylethyl amine. This method can be applied to varieties of amines including sterically hindered amino acid esters in less time with reasonably good yields. HOBt ester of sulfonic acids can be a replacement for pentafluorophenyl and trichlorophenyl ester as well as chloride moiety of sulfonyl chloride for amidation.

Sulfonic acid esters

A novel process for the amidation or esterification which comprises reacting a compound having a carboxy group with a compound having an amino or imino group which can be acylated or with a compound having a hydroxy group in the presence of a sulfonic acid ester of the formula: wherein R1 is an organic group and R2 O-- is a residue of a strongly acidic N-hydroxy compound as a condensation agent, and a novel sulfonic acid ester useful as such a condensation agent and a process for the preparation thereof.