52427-11-9

Basic information

• Product Name: 3-(4-methoxyphenyl)-2-methylpropionic acid
• Synonyms: 3-(4-methoxyphenyl)-2-methylpropionic acid
• CAS NO: 52427-11-9
• Molecular Weight: 194.23
• Mol File: 52427-11-9.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: 3-(4-methoxyphenyl)-2-methylpropionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-methoxyphenyl)-2-methylpropionic acid(52427-11-9)
• EPA Substance Registry System: 3-(4-methoxyphenyl)-2-methylpropionic acid(52427-11-9)

Safety Data

• Hazardous Substances Data: 52427-11-9(Hazardous Substances Data)

Upstream product

• 13048-81-2 (E)-3-(4-methoxyphenyl)-2-methylacrylic acid 
• 140-67-0 Estragole 
• 824-94-2 p-methoxybenzyl chloride 
• 609-08-5 Diethyl methylmalonate 
• 123-11-5 4-methoxy-benzaldehyde 
• 52750-05-7 3-(4-methoxy-phenyl)-2-methyl-acrylic acid ethyl ester 
• 17226-85-6 α-methyl-β-hydroxy-β-(p-methoxyphenyl)ethyl propionate 
• 52750-05-7 ethyl (E)-3-(4-methoxyphenyl)-2-methylpropenoate 
• 105372-24-5 diethyl [(4-methoxyphenyl)methyl](methyl)malonate 
• 148149-45-5 α-methyl-β-(p-methoxy-phenyl)-ethyl propionate 
• 52750-06-8 ethyl 2-methyl-3-[4-(methoxy)phenyl]propanoate 
• 40527-52-4 3-(4-anisyl)-2-methylacrylic acid 
• 64-18-6 formic acid 
• 5462-06-6 3-(p-methoxyphenyl)-2-methylpropionaldehyde 

Downstream Products

• 56935-39-8 α-methyl-β-(p-methoxyphenyl)-propionyl chloride 
• 64-13-1 2-amino-1-(4-methyoxyphenyl)propane 
• 39755-38-9 3-(4'-methoxyphenyl)-2-methyl-propanamide 
• 16204-04-9 [(3Z)-benzylidene-6-methoxy-2-methyl-3H-inden-1-yl]-acetic acid 
• 182116-58-1 2-(3(Z)-benzylidene-6-hydroxy-2-methyl-3H-inden-1-yl)acetamide 
• 177362-72-0 2-(3(Z)-benzylidene-6-methoxy-2-methyl-3H-inden-1-yl)acetamide 
• 182116-61-6 4-{3-Carbamoylmethyl-2-methyl-1-[1-phenyl-meth-(E)-ylidene]-1H-inden-5-yloxy}-butyric acid ethyl ester 
• 5464-10-8 6-methoxy-2-methylindanone 
• 83-33-0 inden-1-one 
• 1346513-36-7 C₂₃H₂₄O₃ 

Relevant articles and documents

A simple method for the synthesis of 2-amino-1(4′-methoxyphenyl)-propane

Synthesis of 2-amino-1-(4′-methoxyphenyl)-propane (II) starting from p-anisaldehyde (1) in 67% overall yield is described. Key reactions involved Horner-Wadswoth-Emmons olefination of 1 to form the ester 2 and Hoffmann degradation of amide 5 to obtain the amine II.

Carbonylative Transformation of Allylarenes with CO Surrogates: Tunable Synthesis of 4-Arylbutanoic Acids, 2-Arylbutanoic Acids, and 4-Arylbutanals

In this Communication, procedures for the selective synthesis of 4-arylbutanoic acids, 2-arylbutanoic acids, and 4-arylbutanals from the same allylbenzenes have been developed. With formic acid or TFBen as the CO surrogate, reactions proceed selectively and effectively under carbon monoxide gas-free conditions.

DERIVATIVES OF SULINDAC CAN PROTECT NORMAL CELLS AGAINST OXIDATIVE DAMAGE

The disclosure provides chemical compounds possessing therapeutic and/or protective properties against oxidative damage. Methods of making such therapeutic and/or protective compounds and associated compositions are also provided, as are methods for their use, which include protecting cells from oxidative damage and/or inhibiting production of ROS in a cell or subject, as well as preventing or reducing the extent of tissue damage caused by an ischemic event in a subject at elevated risk of such an event.