52509-74-7

Basic information

• Product Name: 3,4-dimethylphenyl phenyl ether
• Synonyms: 3,4-dimethylphenyl phenyl ether
• CAS NO: 52509-74-7
• Molecular Weight: 198.265
• Mol File: 52509-74-7.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 3,4-dimethylphenyl phenyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dimethylphenyl phenyl ether(52509-74-7)
• EPA Substance Registry System: 3,4-dimethylphenyl phenyl ether(52509-74-7)

Safety Data

• Hazardous Substances Data: 52509-74-7(Hazardous Substances Data)

Upstream product

• 95-65-8 3,4-Dimethylphenol 
• 108-86-1 bromobenzene 
• 31599-61-8 3,4-dimethyliodobenzene 
• 108-95-2 phenol 
• 108-90-7 chlorobenzene 
• 591-50-4 iodobenzene 
• 100-67-4 potassium phenolate 

Downstream Products

• 37951-15-8 4-phenoxyphthalic acid 

Relevant articles and documents

Efficient catalytic activity of copper/aluminum hydrotalcite in diaryl ether synthesis

A simple copper/aluminum hydrotalcite (Cu/Al-HT) catalyzed arylation of phenols with aryl iodides afforded the corresponding diaryl ethers in moderate to excellent yields. This ligand- free Cu/Al-HT catalyzed coupling of aryl iodides with phenols resulted in high yields of diaryl ethers in the absence of an additive. The catalyst was quantitatively recovered from the reaction by simple filtration and reused for a number of cycles. Georg Thieme Verlag Stuttgart New York.

Chemoselective and ligand-free synthesis of diaryl ethers in aqueous medium using recyclable alumina-supported nickel nanoparticles

An economical and eco-compatible ligand-free protocol for the synthesis of diaryl ethers has been developed using easily accessible alumina-supported nickel nanoparticles as a stable recyclable heterogeneous catalyst in aqueous medium along with a surfactant (SDS) and a mild base (K2CO3). Various sensitive functional groups like allyl, alkoxycarbonyl, formyl, oxo, chloro, bromo, amine and nitro were tolerated in the aforesaid method. Excellent chemoselectivity was demonstrated through competition experiments.

Copper(II) trans-bis-(glycinato): An efficient heterogeneous catalyst for cross coupling of phenols with aryl halides

Copper(II) trans-bis-(glycinato) complex, easily prepared by the solid state reaction of copper(II) acetate and glycine (trans-[Cu(glyo) 2·H2O]) was found to be an efficient, recyclable, and high yielding catalyst for the Ullmann type synthesis of diaryl ethers via the cross coupling of phenols with aryl halides without using any additives at relatively low reaction temperature. The catalyst could easily be recovered by simple filtration and was reused for several runs with consistent catalytic activity.