52715-14-7Relevant articles and documents
Hydroxylated terphenylphosphine ligands for palladium-catalyzed ortho-selective cross-coupling of dibromophenols, dibromoanilines, and their congeners with Grignard reagents
Ishikawa, Shunpei,Manabe, Kei
experimental part, p. 10156 - 10163 (2012/02/13)
p-Terphenylphosphines bearing one or two hydroxy groups were used as ligands to palladium in the cross-coupling of dibromophenols, dibromoanilines, and their congeners with Grignard reagents. High ortho-selectivity that cannot be achieved using other phosphine ligands was observed. ortho-Preference was also observed in competitive cross-coupling reactions of two substrates. A significant effect of the concentration of the Grignard reagent on the ortho-selectivity was observed, when the hydroxylated terphenylphosphines were used. Kinetic studies on this effect showed that high concentrations of the Grignard reagent retard the cross-coupling reaction only at the para-position, but not at the ortho-position.
Ortho-selective cross coupling of dibromophenols and dibromoanilines with grignard reagents in the presence of palladium catalysts bearing hydroxylated oligoarene-type phosphine
Ishikawa, Shunpei,Manabe, Kei
, p. 1304 - 1305 (2008/03/18)
p-Terphenylphosphines with a hydroxy group were used as ligands for palladium in the catalytic cross coupling of dibromophenols and dibromoanilines with Grignard reagents. High ortho-selectivity that cannot be achieved with other phosphine ligands was observed. Copyright
ALKYLATION OF ACTIVE HYDROGEN COMPOUNDS WITH ALLYLIC AND BENZYLIC ALCOHOLS UNDER CoCl2 CATALYSIS. A USEFUL SYNTHESIS OF GRIFOLIN
Marquet, J.,Moreno-Manas, M.
, p. 173 - 176 (2007/10/02)
CoCl2 is a useful catalyst for the condensation of allylic and benzylic alcohols with active hydrogen compounds.Under these neutral conditions orcinol and farnesol react to afford the antibiotic grifolin.