52784-33-5

Basic information

• Product Name: 2-Cyclopenten-1-one, 5-(phenylmethyl)-
• CAS NO: 52784-33-5
• Molecular Formula: C12H12O
• Molecular Weight: 172.227
• Mol File: 52784-33-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-Cyclopenten-1-one, 5-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclopenten-1-one, 5-(phenylmethyl)-(52784-33-5)
• EPA Substance Registry System: 2-Cyclopenten-1-one, 5-(phenylmethyl)-(52784-33-5)

Safety Data

• Hazardous Substances Data: 52784-33-5(Hazardous Substances Data)

Upstream product

• 91791-00-3 3-benzyl-4-thianone 
• 92576-42-6 2-benzyl-pent-4-enoyl chloride 
• 57204-92-9 2-Benzyl-2-phenylselenocyclopentanon 
• 91791-10-5 6-benzyl-1,4-dioxo-8-thiaspiro<4.5>decane 8,8-dioxide 
• 91791-23-0 3-benzyl-3-(methoxycarbony)-4-thianone 
• 91791-05-8 6-Benzyl-1,4-dioxa-8-thia-spiro[4.5]decane 
• 100-39-0 benzyl bromide 
• 4160-61-6 3-methoxycarbonyltetrahydropyran-4-one 
• 930-30-3 cyclopent-2-enone 
• 2867-63-2 2-benzylcyclopentanone 

Relevant articles and documents

Trialkylamine-mediated intramolecular acylation of akenes with carboxylic acid chlorides

Trialkylamine-mediated intramolecular cyclization of pent-4-enoyl chlorides was studied. Substitution with a tertiary alkyl group at the 2-position gave cyclopent-2-en-1-ones, while substitution with an aromatic group gave enol esters, which were formed by O-acylation of initially formed 3-chlorocyclopentanones with ketenes.

A Regioselective Synthesis of Cyclopentenones from 4-Thianone

Alkyl-substituted 3-cyclopentenones 4 and 5 were prepared in moderate to good yields starting from 4-thianone by the selective alkylation and Ramberg-Baecklund-type reactions.One route starts with 6-alkyl-1,4-dioxa-8-thiaspirodecane 8,8-dioxides (8) and another with 7-alkyl-1,4-dioxa-7-(p-tolylsulfonyl)-8-thiaspirodecane 8,8-dioxides (15), followed by acid-catalyzed cleavage of the 1,3-dioxolane ring of 1,4-dioxaspironon-7-enes 9 and 16 to afford 4 and 5.

TETRAHYDROTHIOPYRAN-4-ONE. A USEFUL 5 C SYNTHON FOR THE SYNTHESIS OF 3-CYCLOPENTENONES

2-Alkyl-3-cyclopentenones were prepared in moderate yields starting from tetrahydrothiopyran-4-one by the one-pot Ramberg-Baecklung reaction of 6-alkyl-1,4-dioxa-8-thiaspirodecane-8,8-dioxides, followed by acid catalyzed de-dioxolanation.