52987-31-2

Basic information

• Product Name: N-[2-(3,4-dimethoxyphenyl)-1-methyl-ethyl]formamide
• Synonyms: N-[2-(3,4-dimethoxyphenyl)-1-methyl-ethyl]formamide
• CAS NO: 52987-31-2
• Molecular Weight: 223.272
• Mol File: 52987-31-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-[2-(3,4-dimethoxyphenyl)-1-methyl-ethyl]formamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-(3,4-dimethoxyphenyl)-1-methyl-ethyl]formamide(52987-31-2)
• EPA Substance Registry System: N-[2-(3,4-dimethoxyphenyl)-1-methyl-ethyl]formamide(52987-31-2)

Safety Data

• Hazardous Substances Data: 52987-31-2(Hazardous Substances Data)

Upstream product

• 776-99-8 3,4-dimethoxyphenylacetone 
• 64165-14-6 ammonium hydroformate 
• 64-18-6 formic acid 
• 120-26-3 2-(3,4-dimethoxyphenyl)-1-methylethylamine 
• 109-94-4 formic acid ethyl ester 
• 122-47-4 1-(3,4-dimethoxyphenyl)-2-nitropropene 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 77287-34-4 formamide 

Downstream Products

• 894419-50-2 N-{2-[4,5-dimethoxy-2-(2-oxo-2-phenylethyl)phenyl]-1-methylethyl}formamide 
• 52999-84-5 1-benzyl-6,7-dimethoxy-3-methyl-3,4-dihydro-isoquinoline 
• 894419-49-9 N-[2-(2-acetyl-4,5-dimethoxyphenyl)-1-methylethyl]formamide 
• 87095-05-4 1,3-dimethyl-6,7-dimethoxy-3,4-dihydroisoquinoline 

Relevant articles and documents

Discovery of RG7834: The First-in-Class Selective and Orally Available Small Molecule Hepatitis B Virus Expression Inhibitor with Novel Mechanism of Action

Chronic hepatitis B virus (HBV) infection is a serious public health burden, and current therapies cannot achieve satisfactory cure rate. There are high unmet medical needs of novel therapeutic agents with differentiated mechanism of action (MOA) from the

NOVEL DIHYDROQUINOLIZINONES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION

The invention provides novel compounds having the general formula (I) wherein R1, R2 R3, R4, R5 and R6 are as described herein, compositions including the compounds and methods of using the compounds in the treatment of the hepatitis B virus.

Application of the intramolecular ?-amidoalkylation reaction for the synthesis of 3- and 1,3-alkyl(aryl) 2-formyltetrahydroisoquinolines

3- and 1,3-alkyl(aryl) 2-formyltetrahydroisoquinolines 6 are obtained by the application of the intramolecular ?-amidoalkylation reaction from 1-alkyl(aryl)-2-arylethylformamides 2 and aldehydes in acidic medium.