5317-86-2

Basic information

• Product Name: 3'-(α-Brompropionyl)-methansulfonanilid
• Synonyms: 3'-(α-Brompropionyl)-methansulfonanilid
• CAS NO: 5317-86-2
• Molecular Weight: 306.18
• Mol File: 5317-86-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3'-(α-Brompropionyl)-methansulfonanilid(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-(α-Brompropionyl)-methansulfonanilid(5317-86-2)
• EPA Substance Registry System: 3'-(α-Brompropionyl)-methansulfonanilid(5317-86-2)

Safety Data

• Hazardous Substances Data: 5317-86-2(Hazardous Substances Data)

Upstream product

• 5317-85-1 N-methanesulfonyl-3-aminopropiophenone 
• 1197-05-3 1-(3-amino-phenyl)-propan-1-one 
• 17408-16-1 3'-nitropropiophenone 

Relevant articles and documents

Adrenergic sulfonanilides. 4. Centrally active beta-adrenergic agonists.

The central nervous system (CNS) activities of a number of soterenol analogs have been investigated, and several of these compounds possessed potent morphine antagonistic and anorexiant properties. The CNS activity of these compounds was enhanced by certain lipophilic [e.g., 1,1-dimethyl-2-phenethyl (43) or cyclopropyl (40 and 44)] nitrogen substituents; however, minor structural changes on either the aromatic or side-chain moieties drastically reduced central activity. Toxicity in this series was related to the inherent alpha-adrenergic stimulating component (direct or indirect).