53666-48-1

Basic information

• Product Name: N-(2-chloro-5-nitrophenyl)formamide
• Synonyms: formamide, N-(2-chloro-5-nitrophenyl)-
• CAS NO: 53666-48-1
• Molecular Formula: C₇H₅ClN₂O₃
• Molecular Weight: 200.5792
• Mol File: 53666-48-1.mol
• Article Data: 6

Chemical Properties

• Melting Point: 179-180 °C(Solv: ethanol (64-17-5))
• Boiling Point: 402.9°C at 760 mmHg
• Flash Point: 197.4°C
• Density: 1.542g/cm³
• Vapor Pressure: 1.06E-06mmHg at 25°C
• Refractive Index: 1.651
• PKA: 13.15±0.70(Predicted)
• CAS DataBase Reference: N-(2-chloro-5-nitrophenyl)formamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-chloro-5-nitrophenyl)formamide(53666-48-1)
• EPA Substance Registry System: N-(2-chloro-5-nitrophenyl)formamide(53666-48-1)

Safety Data

• Hazardous Substances Data: 53666-48-1(Hazardous Substances Data)

Upstream product

• 64-18-6 formic acid 
• 97-00-7 1-chloro-2,4-dinitro-benzene 
• 6283-25-6 H₂NC₆H₃(Cl)NO₂ 

Downstream Products

• 1123-93-9 5-aminobenzothiazole 
• 256415-35-7 C₁₄H₁₁N₃S₂ 
• 1360449-09-7 1,3-di(benzo[d]thiazol-5-yl)thiourea 
• 256415-12-0 C₁₄H₁₁N₃OS 
• 2942-07-6 5-nitrobenzothiazole 
• 1173978-56-7 9-chloro-1-(2,4-dichlorophenyl)-6-nitro-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole 
• 143097-22-7 2-(2-chloro-5-nitrophenylimino)-1,2,3,4,5,6-hexahydropyrimidine 
• 1173978-58-9 9-chloro-1-(2,4-dichlorophenyl)-N,N-diethyl-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazol-6-amine 
• 1173978-57-8 9-chloro-1-(2,4-dichlorophenyl)-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazol-6-amine 

Relevant articles and documents

ACTIVATORS OF THE RETINOIC ACID INDUCIBLE GENE "RIG-I' PATHWAY AND METHODS OF USE THEREOF

The present invention is directed to compounds of Formula (I), which are activators of the RIG-I pathway.

Discovery of 1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazoles as novel class of corticotropin releasing factor 1 receptor antagonists

A new class of corticotropin releasing factor 1 (CRF1) receptor antagonists characterized by a tricyclic core ring was designed and synthesized. Novel tricyclic derivatives 2a–e were designed as CRF1 receptor antagonists based on con

PROCESS FOR THE PREPARATION OF N-SUBSTITUTED FORMAMIDES

N-Aryl- or N-heteroarylformamides are prepared by hydrogenating a corresponding nitroarene or nitroheteroarene with formic acid and/or ammonium formate as hydrogen donor and formylating agent in the presence of at least one noble metal-based hydrogenation catalyst and a vanadium or molybdenum compound as co-catalyst.