5447-69-8

Basic information

• Product Name: diethyl (1-phenylpentyl)propanedioate
• CAS NO: 5447-69-8
• Molecular Formula: C₁₈H₂₆O₄
• Molecular Weight: 306.3966
• Mol File: 5447-69-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 378.1°C at 760 mmHg
• Flash Point: 177.9°C
• Density: 1.037g/cm³
• Vapor Pressure: 6.45E-06mmHg at 25°C
• Refractive Index: 1.491
• CAS DataBase Reference: diethyl (1-phenylpentyl)propanedioate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl (1-phenylpentyl)propanedioate(5447-69-8)
• EPA Substance Registry System: diethyl (1-phenylpentyl)propanedioate(5447-69-8)

Safety Data

• Hazardous Substances Data: 5447-69-8(Hazardous Substances Data)

Upstream product

• 88626-90-8 BuMnCl 
• 5292-53-5 diethyl benzalmalonate 
• 97878-04-1 tetraethylammonium bis<α,α-bis(trifluorometyl)benzenemethanolato(2-)-C²,O>-n-butylsilicate(1-) 
• 100-52-7 benzaldehyde 
• 583-03-9 1-Phenyl-1-pentanol 
• 15677-44-8 tributylgallium 
• 127356-65-4 1-phenyl-1-bromopentane 
• 105-53-3 diethyl malonate 
• 996-82-7 sodium diethylmalonate 
• 27059-47-8 1-phenyl-1-chloropentane 

Downstream Products

• 220629-77-6 (1-Phenylpentyl)propanedioic acid 
• 185674-73-1 2-Diazo-5-phenylnonan-3-one 
• 220629-78-7 3-Phenylheptanoyl chloride 
• 5638-30-2 acide 3-phenyl-heptanoique 

Relevant articles and documents

Photocatalytic Giese-Type Reaction with Alkylsilicates Bearing C,O-Bidentate Ligands

Herein, a photocatalytic Giese-type reaction with alkylsilicates bearing C,O-bidentate ligands as stable alkyl radical precursors has been reported. The alkylsilicates were prepared in one step from organometallic reagents. Not only primary, secondary, and tertiary alkyl radicals, but also elusive methyl radicals, could be generated by using the present reaction system. The generated radicals were trapped by electron-deficient olefins bearing various functional groups to give the desired alkyl adducts. The silicon byproduct can be recovered after the photoreaction. The radical generation process was investigated by theoretical calculations, which provided an insight into the facile generation of methyl radicals from methylsilicate bearing C,O-bidentate ligands.

A Desulfurative Strategy for the Generation of Alkyl Radicals Enabled by Visible-Light Photoredox Catalysis

Herein, we present a new desulfurative method for generating primary, secondary, and tertiary alkyl radicals through visible-light photoredox catalysis. A process that involves the generation of N-centered radicals from sulfinamide intermediates, followed by subsequent fragmentation, is critical to forming the corresponding alkyl radical species. This strategy has been successfully applied to conjugate addition reactions that features mild reaction conditions, broad substrate scope (>60 examples), and good functional-group tolerance.

Stereocontrol in the intramolecular Buchner reaction of diazoketones

Rhodium(II) acetate catalysed intramolecular Buchner cyclisation of a series of diazoketones 1 proceeds with excellent diastereoselectivity to produce the trans substituted azulenones 2, which exist as a rapidly equilibrating cycloheptatriene-norcaradiene system, from which the norcaradiene tautomers can be efficiently trapped as PTAD cycloadducts 4. The cyclisation-cycloaddition sequence can be conducted in either a stepwise or a tandem process, leading to the pentacyclic systems 4 as a single diastereomer in each case. In the reaction of diazoketone If intramolecular cyclopropanation competes with cyclisation to the aromatic ring.