5453-10-1

Basic information

• Product Name: 6-AMINO-2-CHLORO-7-METHYLPURINE
• Synonyms: 6-AMINO-2-CHLORO-7-METHYLPURINE;2-CHLORO-6-AMINO-7-METHYL-PURINE;(2-chloro-7-methyl-purin-6-yl)amine;2-chloro-7-methyl-purin-6-amine;2-chloro-7-methylpurin-6-amine
• CAS NO: 5453-10-1
• Molecular Formula: C6H6ClN5
• Molecular Weight: 183.6
• Mol File: 5453-10-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 315.6 °C at 760 mmHg
• Flash Point: 144.6 °C
• Appearance: /
• Density: 1.79 g/cm³
• Vapor Pressure: 0.000434mmHg at 25°C
• Refractive Index: 1.821
• CAS DataBase Reference: 6-AMINO-2-CHLORO-7-METHYLPURINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-AMINO-2-CHLORO-7-METHYLPURINE(5453-10-1)
• EPA Substance Registry System: 6-AMINO-2-CHLORO-7-METHYLPURINE(5453-10-1)

Safety Data

• Hazardous Substances Data: 5453-10-1(Hazardous Substances Data)

Usage

General Description

6-AMINO-2-CHLORO-7-METHYLPURINE is a chemical compound with the molecular formula C6H6ClN5O. It is a derivative of purine and is a potent antagonist at adenosine receptors. 6-AMINO-2-CHLORO-7-METHYLPURINE has been studied for its potential pharmacological applications, including its use as an anti-inflammatory and analgesic agent. 6-AMINO-2-CHLORO-7-METHYLPURINE is also used in research as a tool to study the role of adenosine receptors in various physiological and pathological processes. Additionally, this compound has shown potential for use in the development of new medications for the treatment of conditions such as asthma, pain, and cancer.

InChI:InChI=1/C6H6ClN5/c1-12-2-9-5-3(12)4(8)10-6(7)11-5/h2H,1H3,(H2,8,10,11)

Upstream product

• 2273-93-0 2,6-dichloro-7-methylpurine 
• 53050-28-5 2-chloro-7-methyl-6-purinethione 

Downstream Products

• 77931-42-1 C₁₆H₂₅N₈OP 
• 77931-49-8 C₁₂H₁₈ClN₈OP 
• 104802-77-9 2-thio-6-amino-7-methylpurine 

Relevant articles and documents

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Pharmaceutical composition containing 2-dimethylamino-6-diethyleneimidophosphamido-7-methyl-purine

2-Dimethylamino-6-diethyleneimidophosphamido-7-methylpurine having the formula STR1 A method for preparing 2-dimethylamino-6-diethyleneimido-phosphamido-7-methylpurine consisting of treating theo-bromine with heating to the boiling point and subsequently with phosphorus oxychloride and phosphorus pentachloride. The prepared 2,6-dichloro-7-methylpurine is heated to 50° - 60° C in an aqueous solution of ammonia and the resulting 2-chloro-6-amino-7-methylpurine is reacted, with heating, with a aqueous solution of dimethylamine. The obtained 2-dimethylamino-6-amino-7-methylpurine is reacted, at the boiling point, with either phosphorus oxychloride, or phosphorus pentachloride and formic acid. The resulting 2-dimethylamino-7-methylpurinyl-6-aminophosphoric dichloroanhydride is then treated with ethyleneimine in a medium of an organic solvent in the presence of an acceptor of hydrogen chloride, and the final product is then isolated. A preparation for treating malignant tumors of the haemopoietic system, containing 2-dimethylamino-6-diethyleneimidophosphamido-7-methylpurine as the active principle is provided.