54758-74-6

Basic information

• Product Name: 1-(2-hydroxyphenyl)ethan-1-one O-methyl oxime
• Synonyms: 1-(2-hydroxyphenyl)ethan-1-one O-methyl oxime
• CAS NO: 54758-74-6
• Molecular Weight: 165.192
• Mol File: 54758-74-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-(2-hydroxyphenyl)ethan-1-one O-methyl oxime(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-hydroxyphenyl)ethan-1-one O-methyl oxime(54758-74-6)
• EPA Substance Registry System: 1-(2-hydroxyphenyl)ethan-1-one O-methyl oxime(54758-74-6)

Safety Data

• Hazardous Substances Data: 54758-74-6(Hazardous Substances Data)

Upstream product

• 1313429-84-3 2-(1-(methoxyimino)ethyl)phenyl acetate 
• 98-86-2 acetophenone 
• 3376-33-8 O-methyl acetophenone oxime 

Downstream Products

• 89985-53-5 1-(2-hydroxyphenyl)ethylamine 
• 118-93-4 o-hydroxyacetophenone 
• 95-21-6 2-methyl-1,3-benzoxazole 

Relevant articles and documents

Direct Oxygenation of C-H Bonds through Photoredox and Palladium Catalysis

This report presents the oxygenation of C-H bonds via the merger of photocatalysis and Pd catalysis. Herein, we describe the utilization of a photocatalyst to oxidize an organopalladium(II) intermediate to high-valent PdIII or PdIV intermediates, which promotes the formation of C-O bonds. The demonstrated method works efficiently with various directing groups, such as oxime ether and benzothiazole. The applicability of this direct C-O bond formation method is shown by synthesizing several metal complexes of 2-(benzo[d]thiazol-2-yl)phenol that can be used in organic light-emitting diodes and pharmaceuticals.

Ruthenium(II)-Catalyzed Regioselective C-8 Hydroxylation of 1,2,3,4-Tetrahydroquinolines

Ru(II)-catalyzed chelation-assisted highly regioselective C8-hydroxylation of 1,2,3,4-tretrahydroquinolines has been developed. Various 1,2,3,4-tetrahydroquinolines underwent smooth C8-H hydroxylation with cheap and safe K2S2O8 as the oxidant and oxygen source to furnish the corresponding products in good to excellent yields with high tolerance of the functional groups. The choice of a readily installable and removable N-pyrimidyl directing group is the key to catalysis. Mechanistic studies suggest the involvement of a six-membered ruthenacycle intermediate in the catalytic cycle. The method can also be extended to the direct hydroxylation of other (hetero)arene C-H bonds.