55629-53-3

Basic information

• Product Name: 2-cyano-3-(3-nitrophenyl)prop-2-enamide
• Synonyms: 3-Nitrobenzal cyanoacetamide
• CAS NO: 55629-53-3
• Molecular Formula: C₁₀H₇N₃O₃
• Molecular Weight: 217.1809
• Mol File: 55629-53-3.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 493.5°C at 760 mmHg
• Flash Point: 252.2°C
• Density: 1.421g/cm³
• Vapor Pressure: 7.02E-10mmHg at 25°C
• Refractive Index: 1.663
• CAS DataBase Reference: 2-cyano-3-(3-nitrophenyl)prop-2-enamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-cyano-3-(3-nitrophenyl)prop-2-enamide(55629-53-3)
• EPA Substance Registry System: 2-cyano-3-(3-nitrophenyl)prop-2-enamide(55629-53-3)

Safety Data

• Hazardous Substances Data: 55629-53-3(Hazardous Substances Data)

Upstream product

• 7409-18-9 3-nitrobenzylamine 
• 107-91-5 cyanoacetic acid amide 
• 3395-79-7 m-nitrobenzaldehyde dimethylacetal 
• 109-77-3 malononitrile 
• 99-61-6 3-nitro-benzaldehyde 
• 2826-32-6 3-nitrobenzylidenemalononitrile 

Downstream Products

• 95091-82-0 2-Cyano-3-(1,3-dioxo-indan-2-yl)-3-(3-nitro-phenyl)-propionamide 
• 77214-27-8 C₁₇H₁₂Cl₂N₃O₃P 
• 94640-16-1 (4R,5S)-5-Cyano-2-methyl-4-(3-nitro-phenyl)-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid ethyl ester 
• 94640-16-1 (4R,5R)-5-Cyano-2-methyl-4-(3-nitro-phenyl)-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid ethyl ester 
• 95931-47-8 Methyl 2-acetyl-5-amino-4-cyano-3-(3-nitrophenyl)-5-oxopentanoate 
• 57976-42-8 4-Carbamoyl-4-cyano-3-(3-nitro-phenyl)-2-propionyl-butyric acid ethyl ester 
• 862653-93-8 4-(3-nitrophenyl)-2-oxo-6-phenyl-1,2-dihydropyridine-3-carbonitrile 
• 1378944-91-2 2-amino-4-(3-nitro-phenyl)-5,6,7,8-tetrahydro-naphthalene-1,3-dicarbonitrile 
• 1399697-98-3 2-amino-4-(3-aminophenyl)-5,6,7,8-tetrahydronaphthalene-1,3-dicarbonitrile 
• 1239897-83-6 C₂₂H₁₉ClN₄O₇ 
• 1103594-02-0 5-cyano-3-methyl-4-(3-nitrophenyl)-1-phenyl-7H-pyrazolo[3,4-b]pyridin-6-one 
• 57976-43-9 5-Cyano-2-ethyl-4-(3-nitro-phenyl)-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid ethyl ester 
• 95931-46-7 5-Cyano-2-ethyl-4-(3-nitro-phenyl)-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid ethyl ester 
• 95931-48-9 Methyl 5-cyano-1,4,5,6-tetrahydro-2-methyl-4-(3-nitrophenyl)-6-oxo-3-pyridinecarboxylate 

Relevant articles and documents

Oxidative Olefination of Benzylamine with an Active Methylene Compound Mediated by Hypervalent Iodine (III)

Hypervalent iodine-mediated oxidative olefination of amines with an active methylene compound provides a rapid gateway towards the formation of electrophilic alkenes under mild reaction conditions in good to excellent yields. This is an efficient protocol for the preparation of substituted electrophilic alkenes.

Triflic acid-catalyzed metal-free synthesis of (: E)-2-cyanoacrylamides and 3-substituted azetidine-2,4-diones

A TfOH-catalyzed highly efficient synthesis of biologically active (E)-2-cyanoacrylamides and 3-substituted azetidine-2,4-diones has been reported with 64-94% yields under metal-free conditions. The reaction proceeds through sequential Knoevenagel condens

Cyanoacetamide based barbiturates, thiobarbiturates and their biological studies

Various cyanoacetamide based Knoevenagel adducts were coupled with barbituric acid/thiobarbituric acid and triethylorthoformate via a one pot three component reaction in 2-butanol availing the desired compound in excellent yields. All the synthesized comp