95931-48-9

Basic information

• Product Name: 3-Pyridinecarboxylic acid, 5-cyano-1,4,5,6-tetrahydro-2-methyl-4-(3-nitrophenyl)-6-oxo-, methyl ester
• CAS NO: 95931-48-9
• Molecular Formula: C15H13N3O5
• Molecular Weight: 315.285
• Mol File: 95931-48-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-Pyridinecarboxylic acid, 5-cyano-1,4,5,6-tetrahydro-2-methyl-4-(3-nitrophenyl)-6-oxo-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarboxylic acid, 5-cyano-1,4,5,6-tetrahydro-2-methyl-4-(3-nitrophenyl)-6-oxo-, methyl ester(95931-48-9)
• EPA Substance Registry System: 3-Pyridinecarboxylic acid, 5-cyano-1,4,5,6-tetrahydro-2-methyl-4-(3-nitrophenyl)-6-oxo-, methyl ester(95931-48-9)

Safety Data

• Hazardous Substances Data: 95931-48-9(Hazardous Substances Data)

Upstream product

• 99-61-6 3-nitro-benzaldehyde 
• 105-45-3 acetoacetic acid methyl ester 
• 109-77-3 malononitrile 
• 55629-53-3 2-Cyano-3-(3-nitrophenyl)-2-propenamide 
• 95931-47-8 Methyl 2-acetyl-5-amino-4-cyano-3-(3-nitrophenyl)-5-oxopentanoate 
• 107-91-5 cyanoacetic acid amide 

Downstream Products

• 57976-36-0 2-Methoxy-6-methyl-4-(3-nitrophenyl)pyridine 
• 40034-95-5 6-Methyl-4-(3-nitrophenyl)-2(1H)-pyridinone 
• 95970-38-0 2-Chloro-6-methyl-4-(3-nitro-phenyl)-pyridine 
• 57976-37-1 3-(2-Methoxy-6-methyl-pyridin-4-yl)-phenylamine 
• 40034-66-0 3-(2-Methyl-pyridin-4-yl)-phenylamine 
• 95931-45-6 Methyl 5-cyano-1,6-dihydro-2-methyl-4-(3-nitrophenyl)-6-oxo-3-pyridinecarboxylate 

Relevant articles and documents

Chem-grafted Zn-SSA as an Efficient Heterogeneous Catalyst to Synthesize 2-Pyridinones

Abstract: Chemo-selectivity is always a hard problem in preparing 2-pyridinones. Silica sulfuric acid (SSA) modified with zinc chloride (Zn–SSA) was found to be a high efficient heterogeneous catalyst to solve this problem. Under Zn–SSA and solvent-free conditions, the one-pot cyclocondensation of 1,3-dicarbonyl compounds, malononitrile and arylaldehydes to afford 2-pyridinones was conveniently implemented. The heterogeneous reaction was much efficient and promising in pharmaceutical study and industrial production. Graphical Abstract: Improving chemo-selectivity is always a hard problem in preparing 2-pyridinones. Silica sulfuric acid (SSA) modified with zinc chloride (Zn–SSA) was found to be efficient heterogeneous catalyst to solve this problem. Under Zn-SSA and solvent-free conditions, the one-pot cyclocondensation of 1,3-dicarbonyl compounds, malononitrile and arylaldehydes to afford 2-pyridinones was conveniently implemented. The heterogeneous reaction was much efficient and promising in pharmaceutical study and industrial production.[Figure not available: see fulltext.]

1-Ethyl-1,4-dihydro-4-oxo-7-(pyridinyl)-3-quinolinecarboxylic acids. I. Synthesis of 3- and 4-(3-aminophenyl)pyridine intermediates

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