560076-63-3

Basic information

• Product Name: 1H-Pyrazole,1-(2-furanylcarbonyl)-(9CI)
• Synonyms: 1H-Pyrazole,1-(2-furanylcarbonyl)-(9CI);2-(pyrazol-1-ylcarbonyl)furan;Furan-2-yl(1H-pyrazol-1-yl)methanone
• CAS NO: 560076-63-3
• Molecular Formula: C8H6N2O2
• Molecular Weight: 162.14544
• Product Categories: AMIDE
• Mol File: 560076-63-3.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1H-Pyrazole,1-(2-furanylcarbonyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole,1-(2-furanylcarbonyl)-(9CI)(560076-63-3)
• EPA Substance Registry System: 1H-Pyrazole,1-(2-furanylcarbonyl)-(9CI)(560076-63-3)

Safety Data

• Hazardous Substances Data: 560076-63-3(Hazardous Substances Data)

Usage

Structure

A derivative of pyrazole, a five-membered aromatic ring with two nitrogen atoms at opposite positions, containing a furan ring attached to the pyrazole ring with a carbonyl group at the 2-position.

Usage

In the synthesis of pharmaceuticals and agrochemicals, and as a building block for the development of new materials.

Potential applications

Various fields due to its unique structure and properties.

Upstream product

• 288-13-1 NH-pyrazole 
• 527-69-5 2-furancarbonyl chloride 
• 98-00-0 (2-furyl)methyl alcohol 
• 98-01-1 furfural 
• 88-14-2 2-furanoic acid 

Relevant articles and documents

Nitroxide-Catalyzed Oxidative Amidation of Aldehydes to Yield N-Acyl Azoles Using Sodium Persulfate

A methodology for the oxidative amidation of aldehydes to yield N-acyl azoles is reported. The approach employs sodium persulfate and a catalytic amount of a nitroxide and is applicable to a range of structurally diverse substrates.

Synthesis and antifungal activity evaluation of new heterocycle containing amide derivatives

A series of heterocycle containing amide derivatives (1-28) were synthesised by the combination of acyl chlorides (1a, 2a) and heterocyclic/homocyclic ring containing amines, and their in vitro antifungal activity was evaluated against five plant pathogenic fungi, namely Gibberella zeae, Helminthosporium maydis, Rhizoctonia solani, Botrytis cinerea and Sclerotinia sclerotiorum. Results of antifungal activity analysis indicated that some of the products showed good to excellent antifungal activity, as compound 2 showed excellent activity against G. zeae and R. solani and potent activity against H. maydi, B. cinerea and S. sclerotiorum, and compounds 1, 8 and 10 also displayed excellent antifungal potential against H. maydi, B. cinerea and S. sclerotiorum and good activity against R. solani when compared with the standard carbendazim.