56216-10-5 Usage
Description
3-BIPHENYL-4-YL-3-OXO-PROPIONIC ACID METHYL ESTER is a chemical compound characterized by the molecular formula C18H16O3. It is a propionic acid ester derivative of 3-biphenyl-4-yl-3-oxo-propionic acid, primarily utilized in organic synthesis for introducing the 3-oxo-propionic acid ester functionality into organic molecules. Due to its potential health and safety risks, careful handling and storage are essential.
Uses
Used in Organic Synthesis:
3-BIPHENYL-4-YL-3-OXO-PROPIONIC ACID METHYL ESTER is used as a reagent in organic synthesis for its ability to introduce the 3-oxo-propionic acid ester functionality into various organic molecules. This functionality is crucial for the synthesis of complex organic compounds and pharmaceuticals, enhancing the versatility and applicability of the compound in chemical research and development.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-BIPHENYL-4-YL-3-OXO-PROPIONIC ACID METHYL ESTER is used as a key intermediate in the synthesis of specific drug molecules. Its unique structure allows for the creation of novel compounds with potential therapeutic properties, contributing to the advancement of medicinal chemistry and drug discovery.
Used in Chemical Research:
3-BIPHENYL-4-YL-3-OXO-PROPIONIC ACID METHYL ESTER is employed as a research tool in chemical laboratories to study the reactivity and properties of propionic acid esters. Its use in various chemical reactions provides insights into the mechanisms and pathways involved, furthering the understanding of organic chemistry and its applications in diverse fields.
Check Digit Verification of cas no
The CAS Registry Mumber 56216-10-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,2,1 and 6 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 56216-10:
(7*5)+(6*6)+(5*2)+(4*1)+(3*6)+(2*1)+(1*0)=105
105 % 10 = 5
So 56216-10-5 is a valid CAS Registry Number.
56216-10-5Relevant articles and documents
Enantioselective decarboxylative Mannich reaction of β-keto acids withC-alkynylN-BocN,O-acetals: access to chiral β-keto propargylamines
Chen, Li-Jun,Li, Wei,Shen, Bao-Chun,Sun, Zhong-Wen,Xie, Hui-Ding,Zhang, Cong-Cong
supporting information, p. 8607 - 8612 (2021/10/20)
The chiral keto-substituted propargylamines are an essential class of multifunctional compounds in the field of organic and pharmaceutical synthesis and have attracted considerable attention, but the related synthetic approaches remain limited. Therefore, a concise and efficient method for the enantioselective synthesis of β-keto propargylaminesviachiral phosphoric acid-catalyzed asymmetric Mannich reaction between β-keto acids andC-alkynylN-BocN,O-acetals as easily availableC-alkynyl imine precursors has been demonstrated here, affording a broad scope of β-ketoN-Boc-propargylamines in high yields (up to 97%) with generally high enantioselectivities (up to 97?:?3 er).
Copper-Catalysed Decarboxylative Trifluoromethylation of β-Ketoacids
Xu, Xiaolan,Chen, Huanhuan,He, Jianbo,Xu, Huajian
supporting information, p. 1665 - 1668 (2017/10/05)
An efficient method for Cu-catalyzed decarboxylative trifluoromethylation of β-ketoacids to achieve α-trifluoromethyl ketones was developed. A wide variety of synthetically useful α-trifluoromethyl ketones were obtained in modest to good yields under mild reaction conditions. The present method also exhibits good functional-group compatibility.
Design, synthesis, and evaluation of non-steroidal farnesoid X receptor (FXR) antagonist
Kainuma, Masahiko,Makishima, Makoto,Hashimoto, Yuichi,Miyachi, Hiroyuki
, p. 2587 - 2600 (2007/10/03)
A series of substituted-isoxazole derivatives was prepared as candidate farnesoid X receptor (FXR) antagonists, based on our previously proposed ligand superfamily concept. Structure-activity relationship studies indicated that the shape and the structura
