933799-76-9Relevant articles and documents
Design, synthesis, and evaluation of non-steroidal farnesoid X receptor (FXR) antagonist
Kainuma, Masahiko,Makishima, Makoto,Hashimoto, Yuichi,Miyachi, Hiroyuki
, p. 2587 - 2600 (2007/10/03)
A series of substituted-isoxazole derivatives was prepared as candidate farnesoid X receptor (FXR) antagonists, based on our previously proposed ligand superfamily concept. Structure-activity relationship studies indicated that the shape and the structura