56437-99-1

Basic information

• Product Name: 1-(3-Methylbenzoyl)-3-phenyl(thiourea)
• Synonyms: 1-(3-Methylbenzoyl)-3-phenyl(thiourea);3-Methyl-N-[(phenylamino)thioxomethyl]benzamide;N-(3-Methylbenzoyl)-N'-phenylthiourea
• CAS NO: 56437-99-1
• Molecular Formula: C₁₅H₁₄N₂OS
• Molecular Weight: 270.3495
• Mol File: 56437-99-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.258g/cm³
• Refractive Index: 1.679
• CAS DataBase Reference: 1-(3-Methylbenzoyl)-3-phenyl(thiourea)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-Methylbenzoyl)-3-phenyl(thiourea)(56437-99-1)
• EPA Substance Registry System: 1-(3-Methylbenzoyl)-3-phenyl(thiourea)(56437-99-1)

Safety Data

• Hazardous Substances Data: 56437-99-1(Hazardous Substances Data)

Usage

Structure

Thiourea derivative with a methylbenzoyl group and a phenyl group attached

Biological activities

Exhibits antimicrobial, antifungal, and antiviral properties

Pharmacological properties

Investigated for potential anticancer and anti-inflammatory properties

Therapeutic applications

Compound of interest due to its potential therapeutic applications and biological activities

InChI:InChI=1/C15H14N2OS/c1-11-6-5-7-12(10-11)14(18)17-15(19)16-13-8-3-2-4-9-13/h2-10H,1H3,(H2,16,17,18,19)

Upstream product

• 1711-06-4 3-Methylbenzoyl chloride 
• 1147550-11-5 ammonium thiocyanate 
• 62-53-3 aniline 
• 28115-86-8 3-methylbenzoyl isothiocyanate 

Downstream Products

• 99-36-5 1-methoxycarbonyl-3-methylbenzene 
• 103-85-5 monophenylthiourea 

Relevant articles and documents

Synthesis and bioactivity of some new 1-tolyl-3-aryl-4-methylimidazole-2- thiones

Three series of new 1-(isomeric methyl)benzoyl-3-arylthioureas (1-3a-i) were prepared from 2-, 3-, and 4-methylbenzoyl chlorides via isothiocyanate formation followed by treatment with various substituted anilines. The base-catalyzed condensation of thiou

THE METHANOLYSIS KINETICS AND DISSOCIATION CONSTANTS OF 1-(SUBST. BENZOYL)-3-PHENYLTHIOUREAS

A series of seven 1-(subst. benzoyl)-phenylthioureas have been prepared and their dissociation constants and solvolysis rate constant have been measured in methanol at 25 deg C.The reaction constant found show that the solvolysis rate is limited by the attack of methoxide ion on the benzoyl carbonyl group of the non-dissociated substrate.The polar effect of substituents in benzoyl group is extensively transferred also by the intramolecular hydrogen bond.