56777-24-3

Basic information

• Product Name: BENZYL L-LACTATE
• Synonyms: Benzyl (S)-2-hydroxypropionate~L-Lactic acid benzyl ester;BENZYL (S)-(-)-LACTATE, TECH., 90%;BenzylL-lactate,98%;BENZYL (S)-2-HYDROXYPROPIONATE;l-lactic acid benzyl ester;N-BENZYLLACTATE;(2S)-2-Hydroxypropionic acid benzyl ester;(S)-2-Hydroxypropionic acid benzyl ester
• CAS NO: 56777-24-3
• Molecular Formula: C₁₀H₁₂O₃
• Molecular Weight: 180.2
• Product Categories: Chiral Building Blocks;Esters (Chiral);Synthetic Organic Chemistry;Chiral Building Blocks;Esters;Organic Building Blocks
• Mol File: 56777-24-3.mol
• Article Data: 43

Chemical Properties

• Melting Point: 17 °C
• Boiling Point: 105-109 °C0.1 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.12 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.002mmHg at 25°C
• Refractive Index: n20/D 1.511(lit.)
• Storage Temp.: Refrigerator
• PKA: 13.03±0.20(Predicted)
• Water Solubility: Not miscible or difficult to mix in water.
• BRN: 2048925
• CAS DataBase Reference: BENZYL L-LACTATE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZYL L-LACTATE(56777-24-3)
• EPA Substance Registry System: BENZYL L-LACTATE(56777-24-3)

Safety Data

• Safety Statements: 23-24/25
• WGK Germany: 3
• Hazardous Substances Data: 56777-24-3(Hazardous Substances Data)

Usage

Uses

Benzyl L-lactate is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.

General Description

Benzyl (S)-(-)-lactate may be used in the preparation of (R)-(+)-methyl 7-(1-(benzyloxy)-1-oxopropan-2-yloxy)-2-oxo-2H-chromene-3-carboxylate.

InChI:InChI=1/C10H12O3/c1-8(11)10(12)13-7-9-5-3-2-4-6-9/h2-6,8,11H,7H2,1H3/t8-/m0/s1

Upstream product

• 55895-92-6 benzyl 2-diazopropanoate 
• 100-39-0 benzyl bromide 
• 76-86-8 Triphenylsilyl chloride 
• 2051-96-9 benzyl lactate 
• 849585-22-4 LACTIC ACID 
• 234433-35-3 2,2-di(naphthalen-1-yl)acetic acid 
• 794-94-5 p-Methoxybenzoic anhydride 
• 501-52-0 3-Phenylpropionic acid 
• 98-89-5 Cyclohexanecarboxylic acid 
• 117-34-0 2,2-diphenylacetic acid 
• 93-97-0 benzoic acid anhydride 
• 79-31-2 isobutyric Acid 
• 622-47-9 4-tolylacetic acid 
• 1760-46-9 diphenylacetic anhydride 

Downstream Products

• 2051-96-9 benzyl (R)-Lactate 
• 339201-09-1 (R)-N-benzyloxycarbonyl-N-phthalimidoalanine benzyl ester 
• 546141-60-0 (S)-Azepane-1,2-dicarboxylic acid 2-((R)-1-benzyloxycarbonyl-ethyl) ester 1-tert-butyl ester 
• 638189-67-0 (2S,1'R)-3-[4-(1'-benzyloxycarbonyl-ethoxy)-phenyl]-2-ethoxy-propionic acid ethyl ester 
• 112106-35-1 1-benzyl 4-tert.butyl 3-tert.butyloxycarbonyl-2(S)-methylsuccinate 
• 1091604-06-6 BocPheψ[CON(Pht)](R)AlaOBn 
• 1239453-23-6 C₁₃H₁₄⁽²⁾HBrO₄ 
• 1192622-34-6 C₃₁H₃₆O₇Si 
• 1239453-39-4 C₃₁H₃₆O₇Si 
• 1239453-37-2 C₃₁H₃₆O₇Si 
• 1239453-24-7 C₁₂H₁₁⁽²⁾H₂BrO₄ 
• 1043023-98-8 C₂₈H₃₂O₅Si 
• 1239453-33-8 C₂₉H₃₄O₅Si 
• 2043-43-8 (S)-(-)-lactamide 

Relevant articles and documents

Palmitoyl lactic acid induces adipogenesis and a brown fat-like phenotype in 3T3-L1 preadipocytes

Brown adipose tissue is specialized to generate heat by dissipating chemical energy and may provide novel strategies for obesity treatment in humans. Recently, advances in understanding the pharmacological and dietary agents that contribute to the browning of white adipose tissue have been made to alleviate obesity by promoting energy expenditure. Krill oil is widely used as a health supplement in humans. In this study, the components from krill oil that promote adipogenesis of 3T3-L1 cells were screened to reveal palmitoyl lactic acid (PLA) as a promoter of adipogenesis. The PLA-induced adipocytes contained large number of small lipid droplets. Moreover, similar to the peroxisome proliferator-activated receptor (PPAR)γ agonists, pioglitazone and rosiglitazone, PLA significantly enhances adipogenesis in the presence of dexamethasone compared with PLA alone. Treatment with PLA causes a brown fat-like phenotype in 3T3-L1 cells by enhanced expression of various brown/beige cell-specific genes, such as PR domain containing 16 (Prdm16) and peroxisome proliferative activated receptor, gamma, coactivator 1 alpha (Pgc1a), as well as adiponectin gene. The expression profile of the brown/beige cell-specific genes induced by PLA was similar to that of the PPARγ agonist in 3T3-L1 cells. Our findings suggest that PLA induces a brown fat-like phenotype and, thus, likely has therapeutic potential in treating obesity.

ENDOPARASITIC DEPSIPEPTIDES

The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof (1) wherein each of R1, R2, R3, R4, L1, and L2, are as defined herein. The present invention also contemplates compositions and methods of treatment as an endoparasiticide with a Formula (1) compound.

Functional Models of the Nickel Pincer Nucleotide Cofactor of Lactate Racemase

A novel nickel pincer cofactor was recently discovered in lactate racemase. Reported here are three synthetic nickel pincer complexes that are both structural and functional models of the pincer cofactor in lactate racemase. DFT computations suggest the ipso-carbon atom of the pyridinium pincer ligands act as a hydride acceptor for lactate isomerization, whereas an organometallic pathway involving nickel-mediated β-hydride elimination is less favored.