57743-36-9

Basic information

• Product Name: NSC78689
• Synonyms: NSC78689
• CAS NO: 57743-36-9
• Molecular Formula: C₁₄H₈BrN₃
• Molecular Weight: 298.13742
• Mol File: 57743-36-9.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 531.4°C at 760 mmHg
• Flash Point: 275.2°C
• Appearance: /
• Density: 1.725g/cm³
• Vapor Pressure: 7.67E-11mmHg at 25°C
• Refractive Index: 1.864
• Storage Temp.: 2-8°C
• CAS DataBase Reference: NSC78689(CAS DataBase Reference)
• NIST Chemistry Reference: NSC78689(57743-36-9)
• EPA Substance Registry System: NSC78689(57743-36-9)

Safety Data

• Hazardous Substances Data: 57743-36-9(Hazardous Substances Data)

Usage

General Description

NSC78689 is a chemical compound that has been identified and studied for its potential therapeutic effects. It is also known by its systematic name, 2-(3-(trifluoromethyl)benzyl)-3H-imidazo[4,5-b]pyridine. NSC78689 has been found to possess anti-proliferative and anticancer properties, making it a potential candidate for cancer therapy. Additionally, it has been shown to inhibit the growth of cancer cells by targeting specific cellular pathways. Further research on NSC78689 may lead to the development of novel treatments for cancer and other diseases.

InChI:InChI=1/C14H8BrN3/c15-8-5-6-10-9(7-8)13-14(17-10)18-12-4-2-1-3-11(12)16-13/h1-7H,(H,17,18)

Upstream product

• 87-48-9 5-Bromo-1H-indole-2,3-dione 
• 95-54-5 1,2-diamino-benzene 
• 243-59-4 indophenazine 

Downstream Products

• 109322-19-2 C₂₅H₂₁BrN₆O₂S 
• 109322-18-1 C₂₄H₁₉BrN₆O₂S 
• 109322-29-4 5-(9-Bromo-indolo[2,3-b]quinoxalin-6-ylmethyl)-4-(2-ethoxy-phenyl)-4H-[1,2,4]triazole-3-thiol 
• 109322-20-5 C₂₃H₁₆BrClN₆OS 
• 109322-17-0 C₂₄H₁₉BrN₆OS 
• 109322-28-3 5-(9-Bromo-indolo[2,3-b]quinoxalin-6-ylmethyl)-4-(4-methoxy-phenyl)-4H-[1,2,4]triazole-3-thiol 
• 109343-66-0 5-(9-Bromo-indolo[2,3-b]quinoxalin-6-ylmethyl)-4-(4-chloro-phenyl)-4H-[1,2,4]triazole-3-thiol 
• 109322-16-9 C₂₃H₁₇BrN₆OS 
• 109322-27-2 5-(9-Bromo-indolo[2,3-b]quinoxalin-6-ylmethyl)-4-p-tolyl-4H-[1,2,4]triazole-3-thiol 
• 109322-26-1 5-(9-Bromo-indolo[2,3-b]quinoxalin-6-ylmethyl)-4-phenyl-4H-[1,2,4]triazole-3-thiol 
• 220462-28-2 2-(2-bromoindolo[3,2-b]quinoxalin-5-yl)-N-{[(cyclohexylamino)thioxomethyl]amino}ethanamide 
• 220462-30-6 2-(2-bromoindolo[3,2-b]quinoxalin-5-yl)-N-{[(cyclohexylamino)oxomethyl]amino}ethanamide 

Relevant articles and documents

Features of the reaction of isatin derivatives with ortho-phenylenediamine

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Br?nsted acid hydrotrope combined catalysis in water: a green approach for the synthesis of indoloquinoxalines and bis-tetronic acids

The present work describes the applications of Br?nsted acid hydrotrope combined catalyst (BAHC) as a mild, efficient and reusable catalyst for synthesis of indoloquinoxalines and bis-tetronic acids in water. Using BAHC, we synthesized many indoloquinoxal

Compound taking 6-phenyl-6H-indolo [2, 3-b] quinoxaline as receptor and application thereof

The invention discloses a compound taking 6-phenyl-6H-indolo [2, 3-b] quinoxaline as a receptor, and belongs to the technical field of organic electroluminescent materials. The structural general formula of the compound is shown as a formula (I), wherein R1 is deuterated phenyl or triazine; A is an electron donating group or an electron accepting group. According to the invention, a specific donorgroup or receptor group is introduced to modify 6-phenyl-6H-indolo [2, 3-b] quinoxaline at a specific position to form a brand-new compound; excellent energy transmission capability and charge transmission capability are achieved; the luminescence stability of luminescent devices can be significantly improved, and the compound can be widely applied to OLED luminescent devices and display devicesto be used as a luminescent layer main body material, a hole blocking material, an electron transmission material or a thermal activity delayed fluorescence (TADF) luminescent material. The structuralgeneral formula is shown as formula (I).

β-cyclodextrin mediated synthesis of indole derivatives: reactions of isatins with 2-amino(or 2-thiole)anilines by supramolecular catalysis in water

An elegant, mild, and straightforward strategy for the synthesis of indole derivatives have been accomplished by the biomimetic catalysis for the first time in water under neutral conditions. This supramolecular catalyst oriented methodology provides a sustainable and green protocol for the synthesis of 6H-indolo[2,3-b]quinoxalines and 3H-spiro[benzo[d]thiazole-2,3’-indolin]-2’-one by the reaction of isatin derivatives with 1,2-difunctionalized benzene using β-cyclodextrin (β-CD) as a recoverable and reusable supramolecular catalyst.