579-92-0

Basic information

• Product Name: 2,2'-IMINODIBENZOIC ACID
• Synonyms: 2,2’-dicarboxyldiphenylamine;2,2’-diphenylaminedicarboxylicacid;2,2’-iminodi-benzoicaci;n-(o-carboxyphenyl)-anthranilicaci;vanadox;DIPHENYLAMINE-2,2'-DICARBOXYLIC ACID;2,2'-IMINODIBENZOIC ACID;N-Cinnamoyl-o-tolylhydrorylamine
• CAS NO: 579-92-0
• Molecular Formula: C₁₄H₁₁NO₄
• Molecular Weight: 257.24
• EINECS: 200-258-5
• Mol File: 579-92-0.mol
• Article Data: 36

Chemical Properties

• Melting Point: 298 °C (dec.)(lit.)
• Boiling Point: 400.49°C (rough estimate)
• Flash Point: 236.2°C
• Appearance: /
• Density: 1.2471 (rough estimate)
• Refractive Index: 1.5780 (estimate)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 3.36±0.36(Predicted)
• Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
• Merck: 13,3350
• CAS DataBase Reference: 2,2'-IMINODIBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2'-IMINODIBENZOIC ACID(579-92-0)
• EPA Substance Registry System: 2,2'-IMINODIBENZOIC ACID(579-92-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• RTECS: DH2960000
• Hazardous Substances Data: 579-92-0(Hazardous Substances Data)

Usage

Chemical Properties

light yellow powder or crystals

Uses

Different sources of media describe the Uses of 579-92-0 differently. You can refer to the following data:
1. Instead of diphenylamine in reactions with oxidizing agents. 2,2'-iminodibenzoic acid may be used as an oxidation-reduction indicator in strongly acid solutions.
2. 2,2''-Dicarboxydiphenylamine is used as a reagent in the synthesis of conjugates of muramyldipeptide or normuramyldipeptide with hydroxyacridine/acridone derivatives, used for antitumor activity.

Purification Methods

Crystallise the acid from EtOH. It complexes with Cu2+ , Zn2+ , Cd2+, Co2+ and Ni2+ . [Beilstein 14 H 354, 14 I 545, 14 III 942, 14 IV 1058.]

Upstream product

• 16463-38-0 potassium 2-chlorobenzoate 
• 118-92-3 anthranilic acid 
• 118-91-2 ortho-chlorobenzoic acid 
• 34069-89-1 methyl 2‐[2‐(methoxycarbonyl)phenylamino]benzoate 
• 7732-18-5 water 
• 37960-65-9 potassium anthranilate 
• 584-08-7 potassium carbonate 
• 4418-61-5 5-aminotetrazole 
• 71-41-0 pentan-1-ol 
• 70787-29-0 N-(2-bromo-phenyl)-benzimidic acid-(2-bromo-phenyl ester) 
• 70787-30-3 N,N-bis(2-bromophenyl)benzamide 
• 134-20-3 2-carbomethoxyaniline 
• 610-94-6 2-bromobenzoic acid methyl ester 
• 610-97-9 o-iodo-methyl-benzoic acid 

Downstream Products

• 32615-84-2 2-(2-carbamoylanilino)benzamide 
• 66492-18-0 1-(2-carbamoylphenyl)-2-methyl-4(1H)-quinazolinone 
• 76403-57-1 2,2'-bis(methylcarbamoyl)diphenylamine 
• 70344-50-2 1-(2-carbamoylphenyl)-2-isopropyl-4(1H)-quinazolinone 
• 76403-69-5 2,3-dihydro-2,3-dimethyl-1-<2-(methylcarbamoyl)-phenyl>-4(1H)-quinazolinone 
• 76403-59-3 1-(2-carbamoylphenyl)-2-benzyl-4(1H)-quinazolinone 
• 76403-65-1 2,3-dimethyl-1-<2-(methylcarbamoyl)phenyl>-4-oxoquinazolinium chloride 
• 76403-66-2 2-(chloromethyl)-3-methyl-1-<2-(methylcarbamoyl)phenyl>-4-oxoquinazolinium chloride 
• 1250437-81-0 9,10-dihydro-9-oxo-N-(3-phenoxy-3-phenylpropyl)acridine-4-carboxamide 
• 1250437-76-3 9,10-dihydro-N-methyl-9-oxo-N-(3-oxo-3-phenylpropyl)acridine-4-carboxamide 
• 1250437-84-3 N-(3-chloro-3-phenylpropyl)-9,10-dihydro-N-methyl-9-oxoacridine-4-carboxamide 
• 1250437-74-1 9,10-dihydro-N-(3-hydroxy-3-phenylpropyl)-9-oxoacridine-4-carboxamide 
• 1250437-78-5 9,10-dihydro-9-oxo-N-(3-oxo-3-phenylpropyl)acridine-4-carboxamide 
• 1250437-83-2 N-(3-chloro-3-phenylpropyl)-9,10-dihydro-9-oxoacridine-4-carboxamide 

Relevant articles and documents

Identification of amino acid appended acridines as potential leads to anti-cancer drugs

In order to develop the amino acid appended acridines as potential leads for anticancer drugs, they were subjected to preliminary investigations. Screening through MTT assay as well as the phase contrast micrographs and Confocal images of immunostained C6

Stitching of tyrosine and 10H-acridin-9-one: Turn-ON fluorescence in the narrow pH range 7.4-8.5 and intracellular labelling of cancer cells

We tailored 10H-acridin-9-one and (S)-tyrosine into 3-(4-hydroxyphenyl)-2-[(9-oxo-9,10-dihydroacridine-4-carbonyl) amino]propionic acid (2). 2 underwent pH dependent protonation/deprotonation and the effect was harnessed in terms of change in the fluoresc

Solvothermal synthesis, structure, and fluorescence properties of three d10 polymers assembled from semi-rigid V-shaped aza-bridged multicarboxylate

Hydro(solvo)thermal reactions between a new flexible multicarboxylate ligand, 2,2′-azanediyldibenzoic acid (H2L), and M(OH)2 (M = Cd, Zn) in the presence of different N-donor ancillary ligands, 4,4′-bipyridine (bpy) and pyridine (py)

Bis-aroylhydrazone based on 2,2′-bis substituted diphenylamine for synthesis of new binuclear organotin (IV) complexes: Spectroscopic characterization, crystal structures, in vitro DNA-binding, plasmid DNA cleavage, PCR and cytotoxicity against MCF7 cell

New dinuclear organotin (IV) complexes, Me4Sn2L, Ph4Sn2L and Bu4Sn2L, have been synthesized from reaction of R2SnCl2 (R?=?Me, Ph and Bu) with a 2,2′-bis-substituted di

Bis-substituted diphenylamine arylidene hydrazones for the synthesis of new binuclear organotin(IV) complexes: Crystal structure, DNA cleavage and molecular docking

Five dinuclear organotin(IV) complexes, R4Sn2La (R = Me, Ph) and R4Sn2Lb (R = Me, Ph and Bu) have been synthesized from reaction of R2SnCl2 with 2,4′- and 2,2′-bis-sub