5842-07-9Relevant articles and documents
Synthesis of macroscopic monolithic metal-organic gels for ultra-fast destruction of chemical warfare agents
Li, Heguo,Pan, Hongjie,Tao, Cheng-An,Wang, Lingyun,Yang, Guang,Zhang, Shouxin,Zhou, Chuan
, p. 22125 - 22130 (2021/07/02)
The potential threat that has originated from chemical warfare agents (CWAs) has promoted the development of advanced materials to enhance the protection of civilian and military personnel. Zr-based metal-organic frameworks (Zr-MOFs) have recently been demonstrated as excellent catalysts for decomposing CWAs, but challenges of integrating the microcrystalline powders of Zr-MOFs into monoliths still remain. Herein, we report hierarchically porous monolithic UiO-66-X xerogels for the destruction of CWAs. We found that the UiO-66-NH2xerogel with a larger pore size and a higher surface area than the UiO-66-NH2powder possessed better degradability of 2-chloroethyl ethyl sulfide (2-CEES), which is a sulfur mustard simulant. These UiO-66-X xerogels exhibit outstanding performance for decomposing CWAs. The half-lives of vesicant agent sulfur mustard (HD) and nerve agentO-ethylS-[2-(diisopropylamino)ethyl] methylphosphonothioate (VX) are as short as 14.4 min and 1.5 min, respectively. This work is, to the best of our knowledge, the first report on macroscopic monolithic UiO-66-X xerogels for ultrafast decomposition of CWAs.
Degradation of Paraoxon and the Chemical Warfare Agents VX, Tabun, and Soman by the Metal-Organic Frameworks UiO-66-NH2, MOF-808, NU-1000, and PCN-777
De Koning, Martijn C.,Van Grol, Marco,Breijaert, Troy
supporting information, p. 11804 - 11809 (2017/10/10)
In recent years, Zr-based metal-organic frameworks (MOFs) have been developed that facilitate catalytic degradation of toxic organophosphate agents, such as chemical warfare agents (CWAs). Because of strict regulations, experiments using live agents are not possible for most laboratories and, as a result, simulants are used in the majority of cases. Reports that employ real CWAs are scarce and do not cover the whole spectrum of agents. We here present a comparative study in which UiO-66-NH2, NU-1000, MOF-808, and PCN-777 are evaluated for their effectiveness in the degradation of paraoxon and the chemical warfare agents tabun, VX, and soman, in N-ethylmorpholine buffer (pH 10) as well as in pure water. All MOFs showed excellent ability to degrade the agents under basic conditions. It was further disclosed that tabun is degraded by different mechanisms depending on the conditions. The presence of an amine, either as part of the MOF structure (UiO-66-NH2) or in the agent itself (VX, tabun), is the most important factor governing degradation rates in water. The results show that MOFs have great potential in future protective applications. Although the use of simulants provides valuable information for initial screening and selection of new MOFs, the use of live agents revealed additional mechanisms that should aid the future development of even better catalysts.
Detoxification of Chemical Warfare Agents Using a Zr6-Based Metal–Organic Framework/Polymer Mixture
Moon, Su-Young,Proussaloglou, Emmanuel,Peterson, Gregory W.,DeCoste, Jared B.,Hall, Morgan G.,Howarth, Ashlee J.,Hupp, Joseph T.,Farha, Omar K.
, p. 14864 - 14868 (2016/10/11)
Owing to their high surface area, periodic distribution of metal sites, and water stability, zirconium-based metal–organic frameworks (Zr6-MOFs) have shown promising activity for the hydrolysis of nerve agents GD and VX, as well as the simulant