58438-04-3

Basic information

• Product Name: Boc-3-(2-Naphthyl)-L-alanine
• Synonyms: BOC-ALA(2-NAPH)-OH;BOC-ALA(2-NAPHTHYL)-OH;BOC-ALA-BETA-(2-NAPHTHYL)-OH;BOC-2-NAL-OH;BOC-2-L-NAPHTHYLALANINE;BOC-3-(2-NAPHTHYL)-ALANINE;BOC-3-(2-NAPHTHYL)-L-ALANINE;N-BOC-3-(2-NAPHTHYL)-L-ALANINE
• CAS NO: 58438-04-3
• Molecular Formula: C₁₈H₂₁NO₄
• Molecular Weight: 315.36
• Product Categories: Amino Acids;Alanine [Ala, A];Unusual Amino Acids;Boc-Amino acid series;a-amino
• Mol File: 58438-04-3.mol
• Article Data: 9

Chemical Properties

• Melting Point: 92-95 °C(lit.)
• Boiling Point: 454.92°C (rough estimate)
• Flash Point: 263.6 °C
• Appearance: Off-white/Solid
• Density: 1.2164 (rough estimate)
• Vapor Pressure: 2.58E-11mmHg at 25°C
• Refractive Index: 1.5740 (estimate)
• Storage Temp.: −20°C
• Solubility: soluble in Ethanol
• PKA: 3.88±0.30(Predicted)
• BRN: 4326467
• CAS DataBase Reference: Boc-3-(2-Naphthyl)-L-alanine(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-3-(2-Naphthyl)-L-alanine(58438-04-3)
• EPA Substance Registry System: Boc-3-(2-Naphthyl)-L-alanine(58438-04-3)

Safety Data

• Hazard Codes: Xi
• Safety Statements: 22-24/25
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 58438-04-3(Hazardous Substances Data)

Usage

Chemical Properties

beige to light brown powder

Uses

N-Boc-3-(2-naphthyl)-L-alanine Functions as a reagent for the synthesis of dipeptidyl nitriles as potent and reversible inhibitors of Cathepsin C

InChI:InChI=1/C18H21NO4/c1-18(2,3)23-17(22)19-15(16(20)21)11-12-8-9-13-6-4-5-7-14(13)10-12/h4-10,15H,11H2,1-3H3,(H,19,22)(H,20,21)/t15-/m0/s1

Upstream product

• 939-26-4 2-bromomethylnaphthyl bromide 
• 143218-07-9 ethyl 2-acetylamino-2-cyano-3-(naphthalen-2-yl)propanoate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 63024-44-2 2-Amino-3-naphthalen-2-yl-propionic acid; hydrochloride 
• 636572-72-0 C₂₃H₂₉NO₆ 
• 58438-04-3 N-tert-butoxycarbonyl-3-(2-naphthyl)-alanine 
• 1393112-55-4 (S)-S-ethyl 2-(tert-butoxycarbonylamino)-3-(naphthalen-2-yl)propanethioate 
• 1393112-51-0 (RS)-S-ethyl 2-(tert-butoxycarbonylamino)-3-(naphthalen-2-yl)propanethioate 
• 6960-34-5 L-3-(2-naphthyl)alanine 
• 74651-77-7 2-(tert-butoxycarbonyloxyimino)-2-phenylacetonitrile 
• 172214-89-0 2-Acetylamino-3-naphthalen-2-yl-propionic acid ethyl ester 
• 136015-50-4 2-Acetylamino-2-naphthalen-2-ylmethyl-malonic acid monoethyl ester 
• 37439-99-9 (S)-N-acetyl-3-(2-naphthyl)alanine 
• 37447-33-9 acetylamino-[2]naphthylmethyl-malonic acid diethyl ester 

Downstream Products

• 1027652-85-2 3,5-dimethylbenzyl (2S)-2-t-butyloxycarbonylamino-3-(2-naphthyl)propionate 
• 176896-73-4 methyl (S)-2-[(tert-butoxycarbonyl)amino]-3-(naphthalen-2-yl)propanoate 
• 251308-65-3 (S)-3-Naphthalen-2-ylmethyl-1-(3-phenyl-propyl)-piperazine-2,5-dione 
• 251308-52-8 [((S)-2-Amino-3-naphthalen-2-yl-propionyl)-(3-phenyl-propyl)-amino]-acetic acid methyl ester 
• 251308-92-6 [(S)-2-Naphthalen-2-ylmethyl-3,6-dioxo-4-(3-phenyl-propyl)-piperazin-1-yl]-acetic acid 
• 251308-79-9 [2-naphthalen-2-ylmethyl-3,6-dioxo-4-(3-phenyl-propyl)-piperazin-1-yl]-acetic acid tert-butyl ester 
• 251309-08-7 N-((S)-1-{(S)-1-[Imino-(2,2,5,7,8-pentamethyl-chroman-6-sulfonylamino)-methyl]-piperidin-3-ylmethyl}-2-oxo-2-thiazol-2-yl-ethyl)-2-[(S)-2-naphthalen-2-ylmethyl-3,6-dioxo-4-(3-phenyl-propyl)-piperazin-1-yl]-acetamide 
• 136015-54-8 (S)-3-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-naphthalen-2-yl-propionylamino)-hexanoylamino]-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid 
• 169499-10-9 N-[Boc-3-(2-naphthyl)-L-alanyl]-1-amino-3-methylbutane 
• 1187048-75-4 TPI-1345-169 
• 190908-91-9 (1-(S)-methylcarbamoyl-2-naphthalen-2-yl-ethyl)-carbamic acid tert-butyl ester 
• 92635-09-1 [(S)-2-Naphthalen-2-yl-1-((S)-1-phenyl-ethylcarbamoyl)-ethyl]-carbamic acid tert-butyl ester 
• 1393112-51-0 (RS)-S-ethyl 2-(tert-butoxycarbonylamino)-3-(naphthalen-2-yl)propanethioate 

Relevant articles and documents

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