5875-24-1Relevant articles and documents
Sonochemically induced reaction between water and 3-chloropropionitrile
Farhat,Berchiesi
, p. 3137 - 3140 (1992)
The water-3-chloropropionitrile biphasic system reacts in an ultrasonic bath, producing the corresponding amide, at room temperature. The C-Cl bond does not react; in this sense the attack is selective.
Nitrile biotransformation by whole cells of Aspergillus sp. PTCC 5266
Yousefi,Mohammadi,Habibi,Cheraghi
body text, p. 54 - 59 (2012/03/10)
Aspergillus sp. PTCC 5266 exhibited nitrile-hydrating activity over a broad pH range from 6.0 to 10.0 at 26°C. It hydrated 4-nitrophenylacetonitrile, 2-chlorobenzonitrile and 3-chlorobenzonitrile to their corresponding carboxylic acids and amides, while benzyl cyanide, benzonitrile, 4-tolunitrile, cyclohexanecarbonitrile, 4-chlorobutyronitrile and isobutyronitrile gave carboxylic acids as the sole products. The maximum whole-cell nitrile-hydrating activity was observed at pH 7.0.
4-[diaryl)hydroxymethyl]-1-piperidinealkylcarboxylic acids, salts and esters useful in the treatment of allergic disorders
-
, (2008/06/13)
Novel compounds useful in the treatment of allergic disorders and having the formula: STR1 where Ar and Ar1 are pyridinyl, phenyl, or substituted phenyl and where Y is --OH,--O? M≈ m,--O--loweralkyl, --O--Aryl, or NR1 R2 (R1, R2 =H, loweralkyl, aryl) are herein disclosed.